Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage

BACKGROUND: To examine whether metabotropic glutamate (mGlu) receptors have any role in mechanisms that shape neuronal vulnerability to ischemic damage, we used the 4-vessel occlusion (4-VO) model of transient global ischemia in rats. 4-VO in rats causes a selective death of pyramidal neurons in the...

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Detalles Bibliográficos
Autores principales: Motolese, Marta, Mastroiacovo, Federica, Cannella, Milena, Bucci, Domenico, Gaglione, Anderson, Riozzi, Barbara, Lütjens, Robert, Poli, Sonia M., Celanire, Sylvain, Bruno, Valeria, Battaglia, Giuseppe, Nicoletti, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619332/
https://www.ncbi.nlm.nih.gov/pubmed/26496940
http://dx.doi.org/10.1186/s13041-015-0158-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619332/
https://www.ncbi.nlm.nih.gov/pubmed/26496940
http://dx.doi.org/10.1186/s13041-015-0158-2

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