The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription

BACKGROUND: Inducible nitric oxide synthase (iNOS) metabolizes L-arginine to produce nitric oxide (NO) which was originally identified in myeloid cells as a host defense mechanism against pathogens. Recent studies, however, have revealed that iNOS is often induced in tumor cells and myeloid cells in...

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Detalles Bibliográficos
Autores principales: Simon, Priscilla S., Sharman, Sarah K., Lu, Chunwan, Yang, Dafeng, Paschall, Amy V., Tulachan, Sidhartha S., Liu, Kebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619452/
https://www.ncbi.nlm.nih.gov/pubmed/26497740
http://dx.doi.org/10.1186/s12885-015-1808-6

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