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CD8(+) T Cells Mediate Female-Dominant IL-4 Production and Airway Inflammation in Allergic Asthma
The prevalence and severity of bronchial asthma are higher in females than in males after puberty. Although antigen-specific CD8(+) T cells play an important role in the development of asthma through their suppressive effect on cytokine production, the contribution of CD8(+) T cells to sex differenc...
Autores principales: | Ito, Chihiro, Okuyama-Dobashi, Kaori, Miyasaka, Tomomitsu, Masuda, Chiaki, Sato, Miki, Kawano, Tasuku, Ohkawara, Yuichi, Kikuchi, Toshiaki, Takayanagi, Motoaki, Ohno, Isao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619475/ https://www.ncbi.nlm.nih.gov/pubmed/26488300 http://dx.doi.org/10.1371/journal.pone.0140808 |
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