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Overexpression of Klotho suppresses liver cancer progression and induces cell apoptosis by negatively regulating wnt/β-catenin signaling pathway

BACKGROUND: Klotho is a discovered aging suppressor gene, and its overexpression in mice extends the life span of the animal. Recently, Klotho is also identified as a tumor suppressor gene in variety of tumors; however, the potential role and the antitumor mechanism remain unclarified in liver cance...

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Detalles Bibliográficos
Autores principales:	Sun, Huidong, Gao, Yanchao, Lu, Kemei, Zhao, Guimei, Li, Xuehua, Li, Zhu, Chang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619481/ https://www.ncbi.nlm.nih.gov/pubmed/26499380 http://dx.doi.org/10.1186/s12957-015-0717-0

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