Defining the complementarities between antibodies and haptens to refine our understanding and aid the prediction of a successful binding interaction

BACKGROUND: Low molecular weight haptens (<1000 Da) cannot be recognized by the immune system unless conjugated to larger carrier molecules. Antibodies to these exceptionally small antigens can still be generated with exquisite sensitivity. A detailed understanding at the molecular level of this...

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Detalles Bibliográficos
Autores principales: Al Qaraghuli, Mohammed M., Palliyil, Soumya, Broadbent, Gillian, Cullen, David C., Charlton, Keith A., Porter, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619568/
https://www.ncbi.nlm.nih.gov/pubmed/26498921
http://dx.doi.org/10.1186/s12896-015-0217-x

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