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A Genetic Cascade of let-7-ncl-1-fib-1 Modulates Nucleolar Size and rRNA Pool in Caenorhabditis elegans

Ribosome biogenesis takes place in the nucleolus, the size of which is often coordinated with cell growth and development. However, how metazoans control nucleolar size remains largely unknown. Caenorhabditis elegans provides a good model to address this question owing to distinct tissue distributio...

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Detalles Bibliográficos
Autores principales: Yi, Yung-Hsiang, Ma, Tian-Hsiang, Lee, Li-Wei, Chiou, Pey-Tsyr, Chen, Po-Hsiang, Lee, Ching-Ming, Chu, Yu-De, Yu, Hsiang, Hsiung, Kuei-Ching, Tsai, Yi-Tzang, Lee, Chi-Chang, Chang, Yu-Sun, Chan, Shih-Peng, Tan, Bertrand Chin-Ming, Lo, Szecheng J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619655/
https://www.ncbi.nlm.nih.gov/pubmed/26492166
http://dx.doi.org/10.1371/journal.pgen.1005580