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Membrane Cholesterol Modulates LOX-1 Shedding in Endothelial Cells
The lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a scavenger receptor responsible for ox-LDL recognition, binding and internalization, which is up-regulated during atherogenesis. Its activation triggers endothelium dysfunction and induces inflammation. A soluble form of LOX-1 h...
Autores principales: | Gioia, Magda, Vindigni, Giulia, Testa, Barbara, Raniolo, Sofia, Fasciglione, Giovanni Francesco, Coletta, Massimiliano, Biocca, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619672/ https://www.ncbi.nlm.nih.gov/pubmed/26495844 http://dx.doi.org/10.1371/journal.pone.0141270 |
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