Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2

Crumbs family proteins are apical transmembrane proteins with ancient roles in cell polarity. Mouse Crumbs2 mutants arrest at midgestation with abnormal neural plate morphology and a deficit of mesoderm caused by defects in gastrulation. We identified an ENU-induced mutation, wsnp, that phenocopies...

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Detalles Bibliográficos
Autores principales: Ramkumar, Nitya, Harvey, Beth M., Lee, Jeffrey D., Alcorn, Heather L., Silva-Gagliardi, Nancy F., McGlade, C. Jane, Bestor, Timothy H., Wijnholds, Jan, Haltiwanger, Robert S., Anderson, Kathryn V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619674/
https://www.ncbi.nlm.nih.gov/pubmed/26496195
http://dx.doi.org/10.1371/journal.pgen.1005551

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