LINE-1 Mediated Insertion into Poc1a (Protein of Centriole 1 A) Causes Growth Insufficiency and Male Infertility in Mice

Skeletal dysplasias are a common, genetically heterogeneous cause of short stature that can result from disruptions in many cellular processes. We report the identification of the lesion responsible for skeletal dysplasia and male infertility in the spontaneous, recessive mouse mutant chagun. We det...

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Detalles Bibliográficos
Autores principales: Geister, Krista A., Brinkmeier, Michelle L., Cheung, Leonard Y., Wendt, Jennifer, Oatley, Melissa J., Burgess, Daniel L., Kozloff, Kenneth M., Cavalcoli, James D., Oatley, Jon M., Camper, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619696/
https://www.ncbi.nlm.nih.gov/pubmed/26496357
http://dx.doi.org/10.1371/journal.pgen.1005569

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