Formalin Inactivation of Japanese Encephalitis Virus Vaccine Alters the Antigenicity and Immunogenicity of a Neutralization Epitope in Envelope Protein Domain III

Formalin-inactivated Japanese encephalitis virus (JEV) vaccines are widely available, but the effects of formalin inactivation on the antigenic structure of JEV and the profile of antibodies elicited after vaccination are not well understood. We used a panel of monoclonal antibodies (MAbs) to map th...

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Detalles Bibliográficos
Autores principales: Fan, Yi-Chin, Chiu, Hsien-Chung, Chen, Li-Kuang, Chang, Gwong-Jen J., Chiou, Shyan-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619746/
https://www.ncbi.nlm.nih.gov/pubmed/26495991
http://dx.doi.org/10.1371/journal.pntd.0004167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619746/
https://www.ncbi.nlm.nih.gov/pubmed/26495991
http://dx.doi.org/10.1371/journal.pntd.0004167

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