Cargando…

Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China

Very limited information is available concerning the epidemiology of T. gondii infection in pregnant women in eastern China. Therefore, a case-control study was conducted to estimate the seroprevalence of toxoplasmosis in this population group and to identify risk factors and possible routes of cont...

Descripción completa

Detalles Bibliográficos
Autores principales: Cong, Wei, Dong, Xiao-Yan, Meng, Qing-Feng, Zhou, Na, Wang, Xiang-Yang, Huang, Si-Yang, Zhu, Xing-Quan, Qian, Ai-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619758/
https://www.ncbi.nlm.nih.gov/pubmed/26539465
http://dx.doi.org/10.1155/2015/170278
_version_ 1782397176404508672
author Cong, Wei
Dong, Xiao-Yan
Meng, Qing-Feng
Zhou, Na
Wang, Xiang-Yang
Huang, Si-Yang
Zhu, Xing-Quan
Qian, Ai-Dong
author_facet Cong, Wei
Dong, Xiao-Yan
Meng, Qing-Feng
Zhou, Na
Wang, Xiang-Yang
Huang, Si-Yang
Zhu, Xing-Quan
Qian, Ai-Dong
author_sort Cong, Wei
collection PubMed
description Very limited information is available concerning the epidemiology of T. gondii infection in pregnant women in eastern China. Therefore, a case-control study was conducted to estimate the seroprevalence of toxoplasmosis in this population group and to identify risk factors and possible routes of contamination. Serum samples were collected from 965 pregnant women and 965 age-matched nonpregnant control subjects in Qingdao and Weihai between October 2011 and July 2013. These were screened with enzyme linked immunoassays for the presence of anti-Toxoplasma IgG and anti-Toxoplasma IgM antibodies. 147 (15.2%) pregnant women and 167 (17.3%) control subjects were positive for anti-T. gondii IgG antibodies, while 28 (2.9%) pregnant women and 37 (3.8%) controls were positive for anti-T. gondii IgM antibodies (P = 0.256). There was no significant difference between pregnant women and nonpregnant controls with regard to the seroprevalence of either anti-T. gondii IgG or IgM antibodies. Multivariate analysis showed that T. gondii infection was associated with location, cats in home, contact with cats and dogs, and exposure to soil. The results indicated that the seroprevalence of T. gondii infection in pregnant women is high compared to most other regions of China and other East Asian countries with similar climatic conditions.
format Online
Article
Text
id pubmed-4619758
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-46197582015-11-04 Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China Cong, Wei Dong, Xiao-Yan Meng, Qing-Feng Zhou, Na Wang, Xiang-Yang Huang, Si-Yang Zhu, Xing-Quan Qian, Ai-Dong Biomed Res Int Research Article Very limited information is available concerning the epidemiology of T. gondii infection in pregnant women in eastern China. Therefore, a case-control study was conducted to estimate the seroprevalence of toxoplasmosis in this population group and to identify risk factors and possible routes of contamination. Serum samples were collected from 965 pregnant women and 965 age-matched nonpregnant control subjects in Qingdao and Weihai between October 2011 and July 2013. These were screened with enzyme linked immunoassays for the presence of anti-Toxoplasma IgG and anti-Toxoplasma IgM antibodies. 147 (15.2%) pregnant women and 167 (17.3%) control subjects were positive for anti-T. gondii IgG antibodies, while 28 (2.9%) pregnant women and 37 (3.8%) controls were positive for anti-T. gondii IgM antibodies (P = 0.256). There was no significant difference between pregnant women and nonpregnant controls with regard to the seroprevalence of either anti-T. gondii IgG or IgM antibodies. Multivariate analysis showed that T. gondii infection was associated with location, cats in home, contact with cats and dogs, and exposure to soil. The results indicated that the seroprevalence of T. gondii infection in pregnant women is high compared to most other regions of China and other East Asian countries with similar climatic conditions. Hindawi Publishing Corporation 2015 2015-10-11 /pmc/articles/PMC4619758/ /pubmed/26539465 http://dx.doi.org/10.1155/2015/170278 Text en Copyright © 2015 Wei Cong et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Cong, Wei
Dong, Xiao-Yan
Meng, Qing-Feng
Zhou, Na
Wang, Xiang-Yang
Huang, Si-Yang
Zhu, Xing-Quan
Qian, Ai-Dong
Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China
title Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China
title_full Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China
title_fullStr Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China
title_full_unstemmed Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China
title_short Toxoplasma gondii Infection in Pregnant Women: A Seroprevalence and Case-Control Study in Eastern China
title_sort toxoplasma gondii infection in pregnant women: a seroprevalence and case-control study in eastern china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619758/
https://www.ncbi.nlm.nih.gov/pubmed/26539465
http://dx.doi.org/10.1155/2015/170278
work_keys_str_mv AT congwei toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina
AT dongxiaoyan toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina
AT mengqingfeng toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina
AT zhouna toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina
AT wangxiangyang toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina
AT huangsiyang toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina
AT zhuxingquan toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina
AT qianaidong toxoplasmagondiiinfectioninpregnantwomenaseroprevalenceandcasecontrolstudyineasternchina