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A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men

Introduction. The relationships of the biochemical components in seminal plasma and serum, and their origins and physiological effects in male reproductive system have been poorly understood. Methods. Based on the calibration and quality control measures, 26 biochemical markers, in seminal plasma an...

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Autores principales: Feng, Rui-Xiang, Lu, Jin-Chun, Zhang, Hong-Ye, Lü, Nian-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619868/
https://www.ncbi.nlm.nih.gov/pubmed/26539526
http://dx.doi.org/10.1155/2015/805328
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author Feng, Rui-Xiang
Lu, Jin-Chun
Zhang, Hong-Ye
Lü, Nian-Qing
author_facet Feng, Rui-Xiang
Lu, Jin-Chun
Zhang, Hong-Ye
Lü, Nian-Qing
author_sort Feng, Rui-Xiang
collection PubMed
description Introduction. The relationships of the biochemical components in seminal plasma and serum, and their origins and physiological effects in male reproductive system have been poorly understood. Methods. Based on the calibration and quality control measures, 26 biochemical markers, in seminal plasma and serum samples from 36 male infertility patients with nonazoospermia were detected and compared. Results. Only PA was undetectable in all seminal plasma samples. There were significant differences of all other 24 biochemical markers in seminal plasma and serum (P < 0.05) except for UA (P = 0.214). There were rich proteins in seminal plasma, and globulin accounted for about 90%. There were also abundant enzymes in seminal plasma, and the activities of ALT, AST, AKP, GGT, LDH, CK, and αHBDH in seminal plasma were significantly higher than those in serum while ADA was inversely lower. There were relatively low levels of Glu, TG, TC, and hsCRP in seminal plasma, but Glu was undetectable in 8 of 36 cases. Conclusions. The differences of the levels of biochemical markers in seminal plasma and serum might be associated with the selective secretion of testis, epididymis and male accessory glands, and the specific environment needed for sperm metabolism and function maintenance.
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spelling pubmed-46198682015-11-04 A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men Feng, Rui-Xiang Lu, Jin-Chun Zhang, Hong-Ye Lü, Nian-Qing Biomed Res Int Research Article Introduction. The relationships of the biochemical components in seminal plasma and serum, and their origins and physiological effects in male reproductive system have been poorly understood. Methods. Based on the calibration and quality control measures, 26 biochemical markers, in seminal plasma and serum samples from 36 male infertility patients with nonazoospermia were detected and compared. Results. Only PA was undetectable in all seminal plasma samples. There were significant differences of all other 24 biochemical markers in seminal plasma and serum (P < 0.05) except for UA (P = 0.214). There were rich proteins in seminal plasma, and globulin accounted for about 90%. There were also abundant enzymes in seminal plasma, and the activities of ALT, AST, AKP, GGT, LDH, CK, and αHBDH in seminal plasma were significantly higher than those in serum while ADA was inversely lower. There were relatively low levels of Glu, TG, TC, and hsCRP in seminal plasma, but Glu was undetectable in 8 of 36 cases. Conclusions. The differences of the levels of biochemical markers in seminal plasma and serum might be associated with the selective secretion of testis, epididymis and male accessory glands, and the specific environment needed for sperm metabolism and function maintenance. Hindawi Publishing Corporation 2015 2015-10-11 /pmc/articles/PMC4619868/ /pubmed/26539526 http://dx.doi.org/10.1155/2015/805328 Text en Copyright © 2015 Rui-Xiang Feng et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Feng, Rui-Xiang
Lu, Jin-Chun
Zhang, Hong-Ye
Lü, Nian-Qing
A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men
title A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men
title_full A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men
title_fullStr A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men
title_full_unstemmed A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men
title_short A Pilot Comparative Study of 26 Biochemical Markers in Seminal Plasma and Serum in Infertile Men
title_sort pilot comparative study of 26 biochemical markers in seminal plasma and serum in infertile men
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619868/
https://www.ncbi.nlm.nih.gov/pubmed/26539526
http://dx.doi.org/10.1155/2015/805328
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