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The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons

The molecular composition of the cannabinoid type 1 (CB1) receptor complex beyond the classical G-protein signaling components is not known. Using proteomics on mouse cortex in vivo, we pulled down proteins interacting with CB1 in neurons and show that the CB1 receptor assembles with multiple member...

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Detalles Bibliográficos
Autores principales: Njoo, Christian, Agarwal, Nitin, Lutz, Beat, Kuner, Rohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619884/
https://www.ncbi.nlm.nih.gov/pubmed/26496209
http://dx.doi.org/10.1371/journal.pbio.1002286