The Peptide Vaccine Combined with Prior Immunization of a Conventional Diphtheria-Tetanus Toxoid Vaccine Induced Amyloid β Binding Antibodies on Cynomolgus Monkeys and Guinea Pigs

The reduction of brain amyloid beta (Aβ) peptides by anti-Aβ antibodies is one of the possible therapies for Alzheimer's disease. We previously reported that the Aβ peptide vaccine including the T-cell epitope of diphtheria-tetanus combined toxoid (DT) induced anti-Aβ antibodies, and the prior...

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Detalles Bibliográficos
Autores principales: Yano, Akira, Ito, Kaori, Miwa, Yoshikatsu, Kanazawa, Yoshito, Chiba, Akiko, Iigo, Yutaka, Kashimoto, Yoshinori, Kanda, Akira, Murata, Shinji, Makino, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619934/
https://www.ncbi.nlm.nih.gov/pubmed/26539559
http://dx.doi.org/10.1155/2015/786501

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