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Downregulation of mPGES-1 Expression via EGR1 Plays an Important Role in Inhibition of Caffeine on PGE(2) Synthesis of HBx(+) Hepatocytes

We investigated the mechanism of caffeine in influencing HBx(+) hepatocytes to synthesize PGE(2). The inhibitory effect of caffeine on hepatocyte proliferation increased with increasing caffeine concentrations (200–800 μM) and treatment times (1–7 days), which was first observed at the second test t...

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Detalles Bibliográficos
Autores principales:	Ma, Yan, Wang, Xiaoqian, Tang, Nanhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619973/ https://www.ncbi.nlm.nih.gov/pubmed/26538827 http://dx.doi.org/10.1155/2015/372750

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