Cargando…

Improved intraocular bioavailability of ganciclovir by mucoadhesive polymer based ocular microspheres: development and simulation process in Wistar rats

BACKGROUND: The poor ocular bioavailability of the conventional eye drops is due to lack of corneal permeability, nasolacrimal drainage and metabolic degradation. To overcome this issue, drug encapsulated in mucoadhesive polymer based ocular microspheres have the advantages of improved drug stabilit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kapanigowda, Usha Ganganahalli, Nagaraja, Sree Harsha, Ramaiah, Balakeshwa, Boggarapu, Prakash Rao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620023/ https://www.ncbi.nlm.nih.gov/pubmed/26497653 http://dx.doi.org/10.1186/s40199-015-0132-7

Ejemplares similares

High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice
por: Ramaiah, Balakeshwa, et al.
Publicado: (2016)

An Improvement of the Efficacy of Moxifloxacin HCl for the Treatment of Bacterial Keratitis by the Formulation of Ocular Mucoadhesive Microspheres
por: Dandagi, Panchaxari Mallappa, et al.
Publicado: (2013)

Design and optimization of ganciclovir solid dispersion for improving its bioavailability
por: Gaber, Dalia A., et al.
Publicado: (2022)

Chemotherapeutic drug targeting to lungs by way of microspheres after intravenous administration
por: Sangi, Sibghatullah, et al.
Publicado: (2018)

Mucoadhesive buccal film of almotriptan improved therapeutic delivery in rabbit model
por: Nair, Anroop B., et al.
Publicado: (2020)

Mucoadhesive Particles: A Novel, Prolonged-Release Nanocarrier of Sitagliptin for the Treatment of Diabetics
por: SreeHarsha, Nagaraja, et al.
Publicado: (2019)

The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres
por: Thakral, Naveen K, et al.
Publicado: (2011)

Formulation and evaluation of Bacillus coagulans-loaded hypromellose mucoadhesive microspheres
por: Alli, Sk Md Athar
Publicado: (2011)

Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes
por: Sun, Bin-jia, et al.
Publicado: (2019)

Sulfasalazine-induced drug rash with eosinophilia and systemic symptoms syndrome in a seronegative spondyloarthritis patient: A Case report
por: Sah, Naresh, et al.
Publicado: (2021)

Formulation and Bioavailability of Novel Mucoadhesive Buccal Films for Candesartan Cilexetil in Rats
por: Mady, Omar Y., et al.
Publicado: (2021)

Mucoadhesive Delivery System: A Smart Way to Improve Bioavailability of Nutraceuticals
por: Subramanian, Parthasarathi
Publicado: (2021)

Novel Mucoadhesive Chitosomes as a Platform for Enhanced Oral Bioavailability of Cinnarizine
por: Oransa, Hagar Ahmed, et al.
Publicado: (2022)

Assembling Surfactants-Mucoadhesive Polymer Nanomicelles (ASMP-Nano) for Ocular Delivery of Cyclosporine-A
por: Terreni, Eleonora, et al.
Publicado: (2020)

Formulation, characterization and evaluation of the effect of polymer concentration on the release behavior of insulin-loaded Eudragit(®)-entrapped mucoadhesive microspheres
por: Kenechukwu, Franklin C., et al.
Publicado: (2016)

Ganciclovir ophthalmic gel, 0.15%: a valuable tool for treating ocular herpes
por: Colin, Joseph
Publicado: (2007)

Mucoadhesive PLGA Nanospheres and Nanocapsules for Lactoferrin Controlled Ocular Delivery
por: Varela-Fernández, Rubén, et al.
Publicado: (2022)

Maleimide-Decorated PEGylated Mucoadhesive Liposomes for Ocular Drug Delivery
por: Moiseev, Roman V., et al.
Publicado: (2022)

Improved bioavailability through floating microspheres of lovastatin
por: Kumar, S., et al.
Publicado: (2011)

Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice
por: Michael, Johanna, et al.
Publicado: (2020)

Repeated intraocular crystallization of ganciclovir in one eye after bilateral intravitreal injections: a case report
por: Iu, Lawrence P. L., et al.
Publicado: (2018)

2% Ganciclovir Eye Drops Control Posner-Schlossman Syndrome Relapses With/Without Cytomegalovirus Intraocular Reactivation
por: Sheng, Qilian, et al.
Publicado: (2022)

Nanoparticle formulation by Büchi B-90 Nano Spray Dryer for oral mucoadhesion
por: Harsha, Sree N, et al.
Publicado: (2015)

Formulation and Evaluation of Propranolol Hydrochloride-Loaded Carbopol-934P/Ethyl Cellulose Mucoadhesive Microspheres
por: Patel, Jayvadan, et al.
Publicado: (2010)

Preparation and In Vitro Characterization of Mucoadhesive Hydroxypropyl Guar Microspheres Containing Amlodipine Besylate for Nasal Administration
por: Swamy, N. G. N., et al.
Publicado: (2011)

Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment
por: Wang, Qiyue, et al.
Publicado: (2017)

Ganciclovir/letermovir: Rebound Cytomegalovirus hepatitis, acquired resistance to ganciclovir and nephrotoxicity: case report
Publicado: (2020)

Chitosan Nanoparticles as a Mucoadhesive Drug Delivery System for Ocular Administration
por: Silva, Mariana M., et al.
Publicado: (2017)

Design of Topical Moxifloxacin Mucoadhesive Nanoemulsion for the Management of Ocular Bacterial Infections
por: Youssef, Ahmed Adel Ali, et al.
Publicado: (2022)

Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity
por: Al-Joufi, Fakhria, et al.
Publicado: (2021)

Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo
por: Alkholief, Musaed, et al.
Publicado: (2020)

Enhanced Dissolution and Oral Bioavailability of Cyclosporine A: Microspheres Based on αβ-Cyclodextrins Polymers
por: Lahiani-Skiba, Malika, et al.
Publicado: (2018)

A desensitization protocol to ganciclovir
por: Cernadas, Josefina Rodrigues, et al.
Publicado: (2014)

Nanotechnology-based formulations to amplify intraocular bioavailability
por: Kagkelaris, Konstantinos, et al.
Publicado: (2022)

Zein Nanoparticles Improve the Oral Bioavailability of Curcumin in Wistar Rats
por: Brotons-Canto, Ana, et al.
Publicado: (2021)

Development and optimization of enteric coated mucoadhesive microspheres of duloxetine hydrochloride using 3(2) full factorial design
por: Setia, Anupama, et al.
Publicado: (2013)

Formulation, Statistical Optimization, and In Vivo Pharmacodynamics of Cydonia oblonga Mucilage/Alginate Mucoadhesive Microspheres for the Delivery of Metformin HCl
por: Noreen, Sobia, et al.
Publicado: (2023)

Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems
por: Gupta, Bharti, et al.
Publicado: (2021)

Crystallization after intravitreal ganciclovir injection
por: Choopong, Pitipol, et al.
Publicado: (2010)

Effective Therapeutic Delivery and Bioavailability Enhancement of Pioglitazone Using Drug in Adhesive Transdermal Patch
por: Nair, Anroop B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_66nlchjtcj0e87mvbn02aijrfo