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Improved intraocular bioavailability of ganciclovir by mucoadhesive polymer based ocular microspheres: development and simulation process in Wistar rats

BACKGROUND: The poor ocular bioavailability of the conventional eye drops is due to lack of corneal permeability, nasolacrimal drainage and metabolic degradation. To overcome this issue, drug encapsulated in mucoadhesive polymer based ocular microspheres have the advantages of improved drug stabilit...

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Detalles Bibliográficos
Autores principales:	Kapanigowda, Usha Ganganahalli, Nagaraja, Sree Harsha, Ramaiah, Balakeshwa, Boggarapu, Prakash Rao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620023/ https://www.ncbi.nlm.nih.gov/pubmed/26497653 http://dx.doi.org/10.1186/s40199-015-0132-7

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