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Down-regulation of miR-135b in colon adenocarcinoma induced by a TGF-β receptor I kinase inhibitor (SD-208)

OBJECTIVE(S): Transforming growth factor-β (TGF-β) is involved in colorectal cancer (CRC). The SD-208 acts as an anti-cancer agent in different malignancies via TGF-β signaling. This work aims to show the effect of manipulation of TGF-β signaling on some miRNAs implicated in CRC. MATERIALS AND METHO...

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Detalles Bibliográficos
Autores principales: Akbari, Abolfazl, Ghahremani, Mohammad Hossein, Mobini, Gholam Reza, Abastabar, Mahdi, Akhtari, Javad, Bolhassani, Manzar, Heidari, Mansour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620183/
https://www.ncbi.nlm.nih.gov/pubmed/26523217

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