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Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia

Plant stanol ester is a natural compound which is used as a cholesterol-lowering ingredient in functional foods and food supplements. The safety and efficacy of plant stanol ester have been confirmed in more than 70 published clinical studies and the ingredient is a well-established and widely recom...

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Autores principales: Rosin, Susanna, Ojansivu, Ilkka, Kopu, Aino, Keto-Tokoi, Malin, Gylling, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620290/
https://www.ncbi.nlm.nih.gov/pubmed/26543642
http://dx.doi.org/10.1155/2015/706970
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author Rosin, Susanna
Ojansivu, Ilkka
Kopu, Aino
Keto-Tokoi, Malin
Gylling, Helena
author_facet Rosin, Susanna
Ojansivu, Ilkka
Kopu, Aino
Keto-Tokoi, Malin
Gylling, Helena
author_sort Rosin, Susanna
collection PubMed
description Plant stanol ester is a natural compound which is used as a cholesterol-lowering ingredient in functional foods and food supplements. The safety and efficacy of plant stanol ester have been confirmed in more than 70 published clinical studies and the ingredient is a well-established and widely recommended dietary measure to reduce serum cholesterol. Daily intake of 2 g plant stanols as plant stanol ester lowers LDL-cholesterol by 10%, on average. In Europe, foods with added plant stanol ester have been on the market for 20 years, and today such products are also available in many Asian and American countries. Despite the well-documented efficacy, the full potential in cholesterol reduction may not be reached if plant stanol ester is not used according to recommendations. This review therefore concentrates on the optimal use of plant stanol ester as part of dietary management of hypercholesterolemia. For optimal cholesterol lowering aiming at a lower risk of cardiovascular disease, plant stanol ester should be used daily, in sufficient amounts, with a meal and in combination with other recommended dietary changes.
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spelling pubmed-46202902015-11-05 Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia Rosin, Susanna Ojansivu, Ilkka Kopu, Aino Keto-Tokoi, Malin Gylling, Helena Cholesterol Review Article Plant stanol ester is a natural compound which is used as a cholesterol-lowering ingredient in functional foods and food supplements. The safety and efficacy of plant stanol ester have been confirmed in more than 70 published clinical studies and the ingredient is a well-established and widely recommended dietary measure to reduce serum cholesterol. Daily intake of 2 g plant stanols as plant stanol ester lowers LDL-cholesterol by 10%, on average. In Europe, foods with added plant stanol ester have been on the market for 20 years, and today such products are also available in many Asian and American countries. Despite the well-documented efficacy, the full potential in cholesterol reduction may not be reached if plant stanol ester is not used according to recommendations. This review therefore concentrates on the optimal use of plant stanol ester as part of dietary management of hypercholesterolemia. For optimal cholesterol lowering aiming at a lower risk of cardiovascular disease, plant stanol ester should be used daily, in sufficient amounts, with a meal and in combination with other recommended dietary changes. Hindawi Publishing Corporation 2015 2015-10-12 /pmc/articles/PMC4620290/ /pubmed/26543642 http://dx.doi.org/10.1155/2015/706970 Text en Copyright © 2015 Susanna Rosin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Rosin, Susanna
Ojansivu, Ilkka
Kopu, Aino
Keto-Tokoi, Malin
Gylling, Helena
Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia
title Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia
title_full Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia
title_fullStr Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia
title_full_unstemmed Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia
title_short Optimal Use of Plant Stanol Ester in the Management of Hypercholesterolemia
title_sort optimal use of plant stanol ester in the management of hypercholesterolemia
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620290/
https://www.ncbi.nlm.nih.gov/pubmed/26543642
http://dx.doi.org/10.1155/2015/706970
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