Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia

Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids....

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Autores principales: Oh, Ji Hyun, Oh, Dong Jun, Koo, So-My, Kim, Yang Ki, Kim, Ki Up, Kim, Hyun Jo, Kim, Dong Won, Uh, Soo-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620339/
https://www.ncbi.nlm.nih.gov/pubmed/26508933
http://dx.doi.org/10.4046/trd.2015.78.4.401
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author Oh, Ji Hyun
Oh, Dong Jun
Koo, So-My
Kim, Yang Ki
Kim, Ki Up
Kim, Hyun Jo
Kim, Dong Won
Uh, Soo-Taek
author_facet Oh, Ji Hyun
Oh, Dong Jun
Koo, So-My
Kim, Yang Ki
Kim, Ki Up
Kim, Hyun Jo
Kim, Dong Won
Uh, Soo-Taek
author_sort Oh, Ji Hyun
collection PubMed
description Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids. A few reports showed treatment failure with macrolides in patients with COP who were resistant to steroids. In this report, we described two cases of COP who showed different responses to clarithromycin. One recovered completely, but the other gradually showed lung fibrosis with clarithromycin.
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spelling pubmed-46203392015-10-27 Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia Oh, Ji Hyun Oh, Dong Jun Koo, So-My Kim, Yang Ki Kim, Ki Up Kim, Hyun Jo Kim, Dong Won Uh, Soo-Taek Tuberc Respir Dis (Seoul) Case Report Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids. A few reports showed treatment failure with macrolides in patients with COP who were resistant to steroids. In this report, we described two cases of COP who showed different responses to clarithromycin. One recovered completely, but the other gradually showed lung fibrosis with clarithromycin. The Korean Academy of Tuberculosis and Respiratory Diseases 2015-10 2015-10-01 /pmc/articles/PMC4620339/ /pubmed/26508933 http://dx.doi.org/10.4046/trd.2015.78.4.401 Text en Copyright©2015. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Case Report
Oh, Ji Hyun
Oh, Dong Jun
Koo, So-My
Kim, Yang Ki
Kim, Ki Up
Kim, Hyun Jo
Kim, Dong Won
Uh, Soo-Taek
Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
title Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
title_full Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
title_fullStr Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
title_full_unstemmed Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
title_short Different Responses to Clarithromycin in Patients with Cryptogenic Organizing Pneumonia
title_sort different responses to clarithromycin in patients with cryptogenic organizing pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620339/
https://www.ncbi.nlm.nih.gov/pubmed/26508933
http://dx.doi.org/10.4046/trd.2015.78.4.401
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