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Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact

All around the world a few studies have been found on the effect of guideline implementation on direct medications’ expenditure. The goal of this study was to evaluate cost savings of guideline implementation among patients who had to receive 3 costly medications including albumin, enoxaparin, and p...

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Autores principales: Mahmoudi, Laleh, Karamikhah, Razieh, Mahdavinia, Azadeh, Samiei, Hasan, Petramfar, Peyman, Niknam, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620749/
https://www.ncbi.nlm.nih.gov/pubmed/26496288
http://dx.doi.org/10.1097/MD.0000000000001744
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author Mahmoudi, Laleh
Karamikhah, Razieh
Mahdavinia, Azadeh
Samiei, Hasan
Petramfar, Peyman
Niknam, Ramin
author_facet Mahmoudi, Laleh
Karamikhah, Razieh
Mahdavinia, Azadeh
Samiei, Hasan
Petramfar, Peyman
Niknam, Ramin
author_sort Mahmoudi, Laleh
collection PubMed
description All around the world a few studies have been found on the effect of guideline implementation on direct medications’ expenditure. The goal of this study was to evaluate cost savings of guideline implementation among patients who had to receive 3 costly medications including albumin, enoxaparin, and pantoprazole in a tertiary hospital in Shiraz, Iran. An 8-month prospective study was performed in 2 groups; group 1 as an observational group (control group) in 4 months from June to September 2014 and group 2 as an interventional group from October 2014 to January 2015. For group 1 the pattern of costly medications usage was determined without any intervention. For group 2, after guideline implementation, the economic impact was evaluated by making comparisons between the data achieved from the 2 groups. A total of 12,680 patients were evaluated during this study (6470 in group 1; 6210 in group 2). The reduction in the total value of costly administered drugs was 56% after guideline implementation. Such reduction in inappropriate prescribing accounts for the saving of 85,625 United States dollars (USD) monthly and estimated 1,027,500 USD annually. Guideline implementation could improve the adherence of evidence-based drug utilization and resulted in significant cost savings in a major teaching medical center via a decrease in inappropriate prescribing of costly medications.
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spelling pubmed-46207492015-10-27 Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact Mahmoudi, Laleh Karamikhah, Razieh Mahdavinia, Azadeh Samiei, Hasan Petramfar, Peyman Niknam, Ramin Medicine (Baltimore) 6600 All around the world a few studies have been found on the effect of guideline implementation on direct medications’ expenditure. The goal of this study was to evaluate cost savings of guideline implementation among patients who had to receive 3 costly medications including albumin, enoxaparin, and pantoprazole in a tertiary hospital in Shiraz, Iran. An 8-month prospective study was performed in 2 groups; group 1 as an observational group (control group) in 4 months from June to September 2014 and group 2 as an interventional group from October 2014 to January 2015. For group 1 the pattern of costly medications usage was determined without any intervention. For group 2, after guideline implementation, the economic impact was evaluated by making comparisons between the data achieved from the 2 groups. A total of 12,680 patients were evaluated during this study (6470 in group 1; 6210 in group 2). The reduction in the total value of costly administered drugs was 56% after guideline implementation. Such reduction in inappropriate prescribing accounts for the saving of 85,625 United States dollars (USD) monthly and estimated 1,027,500 USD annually. Guideline implementation could improve the adherence of evidence-based drug utilization and resulted in significant cost savings in a major teaching medical center via a decrease in inappropriate prescribing of costly medications. Wolters Kluwer Health 2015-10-23 /pmc/articles/PMC4620749/ /pubmed/26496288 http://dx.doi.org/10.1097/MD.0000000000001744 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 6600
Mahmoudi, Laleh
Karamikhah, Razieh
Mahdavinia, Azadeh
Samiei, Hasan
Petramfar, Peyman
Niknam, Ramin
Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact
title Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact
title_full Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact
title_fullStr Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact
title_full_unstemmed Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact
title_short Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact
title_sort implementation of pharmaceutical practice guidelines by a project model based: clinical and economic impact
topic 6600
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620749/
https://www.ncbi.nlm.nih.gov/pubmed/26496288
http://dx.doi.org/10.1097/MD.0000000000001744
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