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Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact
All around the world a few studies have been found on the effect of guideline implementation on direct medications’ expenditure. The goal of this study was to evaluate cost savings of guideline implementation among patients who had to receive 3 costly medications including albumin, enoxaparin, and p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620749/ https://www.ncbi.nlm.nih.gov/pubmed/26496288 http://dx.doi.org/10.1097/MD.0000000000001744 |
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author | Mahmoudi, Laleh Karamikhah, Razieh Mahdavinia, Azadeh Samiei, Hasan Petramfar, Peyman Niknam, Ramin |
author_facet | Mahmoudi, Laleh Karamikhah, Razieh Mahdavinia, Azadeh Samiei, Hasan Petramfar, Peyman Niknam, Ramin |
author_sort | Mahmoudi, Laleh |
collection | PubMed |
description | All around the world a few studies have been found on the effect of guideline implementation on direct medications’ expenditure. The goal of this study was to evaluate cost savings of guideline implementation among patients who had to receive 3 costly medications including albumin, enoxaparin, and pantoprazole in a tertiary hospital in Shiraz, Iran. An 8-month prospective study was performed in 2 groups; group 1 as an observational group (control group) in 4 months from June to September 2014 and group 2 as an interventional group from October 2014 to January 2015. For group 1 the pattern of costly medications usage was determined without any intervention. For group 2, after guideline implementation, the economic impact was evaluated by making comparisons between the data achieved from the 2 groups. A total of 12,680 patients were evaluated during this study (6470 in group 1; 6210 in group 2). The reduction in the total value of costly administered drugs was 56% after guideline implementation. Such reduction in inappropriate prescribing accounts for the saving of 85,625 United States dollars (USD) monthly and estimated 1,027,500 USD annually. Guideline implementation could improve the adherence of evidence-based drug utilization and resulted in significant cost savings in a major teaching medical center via a decrease in inappropriate prescribing of costly medications. |
format | Online Article Text |
id | pubmed-4620749 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-46207492015-10-27 Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact Mahmoudi, Laleh Karamikhah, Razieh Mahdavinia, Azadeh Samiei, Hasan Petramfar, Peyman Niknam, Ramin Medicine (Baltimore) 6600 All around the world a few studies have been found on the effect of guideline implementation on direct medications’ expenditure. The goal of this study was to evaluate cost savings of guideline implementation among patients who had to receive 3 costly medications including albumin, enoxaparin, and pantoprazole in a tertiary hospital in Shiraz, Iran. An 8-month prospective study was performed in 2 groups; group 1 as an observational group (control group) in 4 months from June to September 2014 and group 2 as an interventional group from October 2014 to January 2015. For group 1 the pattern of costly medications usage was determined without any intervention. For group 2, after guideline implementation, the economic impact was evaluated by making comparisons between the data achieved from the 2 groups. A total of 12,680 patients were evaluated during this study (6470 in group 1; 6210 in group 2). The reduction in the total value of costly administered drugs was 56% after guideline implementation. Such reduction in inappropriate prescribing accounts for the saving of 85,625 United States dollars (USD) monthly and estimated 1,027,500 USD annually. Guideline implementation could improve the adherence of evidence-based drug utilization and resulted in significant cost savings in a major teaching medical center via a decrease in inappropriate prescribing of costly medications. Wolters Kluwer Health 2015-10-23 /pmc/articles/PMC4620749/ /pubmed/26496288 http://dx.doi.org/10.1097/MD.0000000000001744 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | 6600 Mahmoudi, Laleh Karamikhah, Razieh Mahdavinia, Azadeh Samiei, Hasan Petramfar, Peyman Niknam, Ramin Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact |
title | Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact |
title_full | Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact |
title_fullStr | Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact |
title_full_unstemmed | Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact |
title_short | Implementation of Pharmaceutical Practice Guidelines by a Project Model Based: Clinical and Economic Impact |
title_sort | implementation of pharmaceutical practice guidelines by a project model based: clinical and economic impact |
topic | 6600 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620749/ https://www.ncbi.nlm.nih.gov/pubmed/26496288 http://dx.doi.org/10.1097/MD.0000000000001744 |
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