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Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor

G protein-coupled receptor kinases (GRKs) have been implicated in human diseases ranging from heart failure to diabetes. Previous studies have identified several compounds that selectively inhibit GRK2, such as paroxetine and balanol. Far fewer selective inhibitors have been reported for GRK5, a tar...

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Detalles Bibliográficos
Autores principales:	Homan, Kristoff T., Wu, Emily, Cannavo, Alessandro, Koch, Walter J., Tesmer, John J. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621012/ https://www.ncbi.nlm.nih.gov/pubmed/25340299 http://dx.doi.org/10.3390/molecules191016937

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