Cargando…

miR-221 Promotes Epithelial-Mesenchymal Transition through Targeting PTEN and Forms a Positive Feedback Loop with β-catenin/c-Jun Signaling Pathway in Extra-Hepatic Cholangiocarcinoma

Extrahepatic cholangiocarcinoma (EHCC) is a refractory malignancy with poor prognosis due to its early invasion, metastasis and recurrence after operation. Therefore, understanding the mechanisms of invasion and metastasis is the key to the development of new and effective therapeutic strategies for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jianguo, Yao, Lei, Li, Guodong, Ma, Donglai, Sun, Chen, Gao, Shuang, Zhang, Ping, Gao, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621024/ https://www.ncbi.nlm.nih.gov/pubmed/26501139 http://dx.doi.org/10.1371/journal.pone.0141168

Ejemplares similares

White Spot Syndrome Virus Establishes a Novel IE1/JNK/c-Jun Positive Feedback Loop to Drive Replication
por: Wang, Sheng, et al.
Publicado: (2019)

MicroRNA-4476 promotes glioma progression through a miR-4476/APC/β-catenin/c-Jun positive feedback loop
por: Lin, Jie, et al.
Publicado: (2020)

miRNA-221 promotes cutaneous squamous cell carcinoma progression by targeting PTEN
por: Gong, Zhen-Hua, et al.
Publicado: (2019)

Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction
por: Gan, Xiao-qing, et al.
Publicado: (2008)

JUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis
por: Jia, Qunying, et al.
Publicado: (2023)

circ_100984‐miR‐432‐3p axis regulated c‐Jun/YBX‐1/β‐catenin feedback loop promotes bladder cancer progression
por: Tong, Liang, et al.
Publicado: (2021)

ITGB1-DT Facilitates Lung Adenocarcinoma Progression via Forming a Positive Feedback Loop With ITGB1/Wnt/β-Catenin/MYC
por: Chang, Ruimin, et al.
Publicado: (2021)

Macrophages-aPKC(ɩ)-CCL5 Feedback Loop Modulates the Progression and Chemoresistance in Cholangiocarcinoma
por: Yang, Tao, et al.
Publicado: (2022)

An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development
por: Wang, Rui, et al.
Publicado: (2021)

Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis
por: Zhang, Mingming, et al.
Publicado: (2019)

Circular RNA VRK1 facilitates pre‐eclampsia progression via sponging miR‐221‐3P to regulate PTEN/Akt
por: Li, Ziwei, et al.
Publicado: (2021)

miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop
por: Zhang, Feifei, et al.
Publicado: (2018)

MicroRNA-221-3p Plays an Oncogenic Role in Gastric Carcinoma by Inhibiting PTEN Expression
por: Shi, Jianping, et al.
Publicado: (2017)

Trail Resistance Induces Epithelial-Mesenchymal Transition and Enhances Invasiveness by Suppressing PTEN via miR-221 in Breast Cancer
por: Wang, Haiji, et al.
Publicado: (2014)

C-Jun drives melanoma progression in PTEN wild type melanoma cells
por: Kappelmann-Fenzl, Melanie, et al.
Publicado: (2019)

Correction to: Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis
por: Zhang, Mingming, et al.
Publicado: (2019)

Positive feedback loop of hepatoma-derived growth factor and β-catenin promotes carcinogenesis of colorectal cancer
por: Lian, Jiayan, et al.
Publicado: (2015)

Correction: Trail Resistance Induces Epithelial-Mesenchymal Transition and Enhances Invasiveness by Suppressing PTEN via miR-221 in Breast Cancer
por: Wang, Haiji, et al.
Publicado: (2019)

LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6(high) cervical cancer stem cells
por: Feng, Qian, et al.
Publicado: (2021)

A Positive Feedback Loop of Hippo- and c-Jun-Amino-Terminal Kinase Signaling Pathways Regulates Amyloid-Beta-Mediated Neurodegeneration
por: Irwin, Madison, et al.
Publicado: (2020)

BUB1B promotes extrahepatic cholangiocarcinoma progression via JNK/c-Jun pathways
por: Jiao, Chen Yu, et al.
Publicado: (2021)

Targeting c-MET by Tivantinib through synergistic activation of JNK/c-jun pathway in cholangiocarcinoma
por: Wei, Kai, et al.
Publicado: (2019)

Ligustrazine eases lung cancer by regulating PTEN and Wnt/β-catenin pathway
por: Dong, Yuehua, et al.
Publicado: (2020)

HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer
por: Mardente, S., et al.
Publicado: (2015)

MicroRNA-221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN
por: Zhang, Lingyan, et al.
Publicado: (2021)

MicroRNA‐221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling
por: Yin, Yingchun, et al.
Publicado: (2020)

HMGA1-TRIP13 axis promotes stemness and epithelial mesenchymal transition of perihilar cholangiocarcinoma in a positive feedback loop dependent on c-Myc
por: Li, Zhipeng, et al.
Publicado: (2021)

miR-22 Forms a Regulatory Loop in PTEN/AKT Pathway and Modulates Signaling Kinetics
por: Bar, Nadav, et al.
Publicado: (2010)

ERp29 forms a feedback regulation loop with microRNA-135a-5p and promotes progression of colorectal cancer
por: Huang, Jiebin, et al.
Publicado: (2021)

A positive feedback loop of the TAZ/β-catenin axis promotes Helicobacter pylori-associated gastric carcinogenesis
por: Xu, Xinbo, et al.
Publicado: (2022)

LTF Induces Radioresistance by Promoting Autophagy and Forms an AMPK/SP2/NEAT1/miR-214-5p Feedback Loop in Lung Squamous Cell Carcinoma
por: Wen, Junmiao, et al.
Publicado: (2023)

On the Extra-Peritoneal Form of Extra-Uterine Gestation
por: Hart, D. Berry
Publicado: (1893)

MOZ Forms an Autoregulatory Feedback Loop with miR-223 in AML and Monocyte/Macrophage Development
por: Jiang, Ming, et al.
Publicado: (2018)

MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
por: Chun-zhi, Zhang, et al.
Publicado: (2010)

MiR-221 promotes trastuzumab-resistance and metastasis in HER2-positive breast cancers by targeting PTEN
por: Ye, Xingming, et al.
Publicado: (2014)

The LIN28B/TGF-β/TGFBI feedback loop promotes cell migration and tumour initiation potential in cholangiocarcinoma
por: Puthdee, Nattapong, et al.
Publicado: (2021)

C9orf140, a novel Axin1-interacting protein, mediates the negative feedback loop of Wnt/β-catenin signaling
por: Jiang, Jun, et al.
Publicado: (2018)

miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR–p-PI3K/AKT-c-JUN
por: Zhao, Mengyang, et al.
Publicado: (2016)

Targeting therapy-resistant lung cancer stem cells via disruption of the AKT/TSPYL5/PTEN positive-feedback loop
por: Kim, In-Gyu, et al.
Publicado: (2021)

Transcriptional Feedback Loops in the Caprine Circadian Clock System
por: Gao, Dengke, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ujf33hemtshqmvvhjp8vt5ctoi