Adenoviral delivery of truncated MMP-8 fused with the hepatocyte growth factor mutant 1K1 ameliorates liver cirrhosis and promotes hepatocyte proliferation

Liver cirrhosis is a chronic liver disease caused by chronic liver injury, which activates hepatic stellate cells (HSCs) and the secretion of extracellular matrix (ECM). Cirrhosis accounts for an extensive level of morbidity and mortality worldwide, largely due to lack of effective treatment options...

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Detalles Bibliográficos
Autores principales: Liu, Jinghua, Li, Jianbo, Fu, Weiwei, Tang, Jiacheng, Feng, Xu, Chen, Jiang, Liang, Yuelong, Jin, Ren’an, Xie, Anyong, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621191/
https://www.ncbi.nlm.nih.gov/pubmed/26527860
http://dx.doi.org/10.2147/DDDT.S92481

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