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Association between pre-miR-27a functional polymorphism and risk of colorectal cancer in north Chinese Han population

MicroRNA-27a (miR-27a) is deemed as an oncogene in malignancies including colorectal cancer (CRC), and rs895819 within pre-miR-27a may affect its secondary structure, leading to its aberrant expression and dysfunction of its targeted gene. We investigated genotype and allele frequencies of the locus...

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Detalles Bibliográficos
Autores principales: Bian, Quan, Chen, Jian-Jun, Gu, Jun-Ping, Xu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621200/
https://www.ncbi.nlm.nih.gov/pubmed/26527885
http://dx.doi.org/10.2147/OTT.S89754