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Epidemiology and treatment of osteoporosis in women: an Indian perspective

The number of women with osteoporosis, ie, with reduced bone mass and the disruption of bone architecture, is increasing in India. While data on prevalence of osteoporosis among women in India come from studies conducted in small groups spread across the country, estimates suggest that of the 230 mi...

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Autores principales: Khadilkar, Anuradha V, Mandlik, Rubina M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621228/
https://www.ncbi.nlm.nih.gov/pubmed/26527900
http://dx.doi.org/10.2147/IJWH.S54623
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author Khadilkar, Anuradha V
Mandlik, Rubina M
author_facet Khadilkar, Anuradha V
Mandlik, Rubina M
author_sort Khadilkar, Anuradha V
collection PubMed
description The number of women with osteoporosis, ie, with reduced bone mass and the disruption of bone architecture, is increasing in India. While data on prevalence of osteoporosis among women in India come from studies conducted in small groups spread across the country, estimates suggest that of the 230 million Indians expected to be over the age of 50 years in 2015, 20%, ie, ~46 million, are women with osteoporosis. Thus, osteoporosis is a major public health problem in Indian women. Low calcium intakes with extensive prevalence of vitamin D deficiency, increasing longevity, sex inequality, early menopause, genetic predisposition, lack of diagnostic facilities, and poor knowledge of bone health have contributed toward the high prevalence of osteoporosis. Bone health may be optimized by creating an environment to achieve peak bone mass during adolescence, maintenance of healthy bone throughout the life cycle, and prevention of bone loss postmenopausal. In Indian women, calcium, vitamin D, and bisphosphonates are the commonest first-line therapies used. The use of other drugs such as hormone replacement therapy, estrogen agonists, calcitonin, parathyroid hormone, and denosumab is decided as per the affordability and availability of treatment options. Major gaps still remain in the diagnosis and management of osteoporosis, thus highlighting the need for more structured research in this area. This review focuses on the epidemiology of osteoporosis in Indian women and available treatments.
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spelling pubmed-46212282015-11-02 Epidemiology and treatment of osteoporosis in women: an Indian perspective Khadilkar, Anuradha V Mandlik, Rubina M Int J Womens Health Review The number of women with osteoporosis, ie, with reduced bone mass and the disruption of bone architecture, is increasing in India. While data on prevalence of osteoporosis among women in India come from studies conducted in small groups spread across the country, estimates suggest that of the 230 million Indians expected to be over the age of 50 years in 2015, 20%, ie, ~46 million, are women with osteoporosis. Thus, osteoporosis is a major public health problem in Indian women. Low calcium intakes with extensive prevalence of vitamin D deficiency, increasing longevity, sex inequality, early menopause, genetic predisposition, lack of diagnostic facilities, and poor knowledge of bone health have contributed toward the high prevalence of osteoporosis. Bone health may be optimized by creating an environment to achieve peak bone mass during adolescence, maintenance of healthy bone throughout the life cycle, and prevention of bone loss postmenopausal. In Indian women, calcium, vitamin D, and bisphosphonates are the commonest first-line therapies used. The use of other drugs such as hormone replacement therapy, estrogen agonists, calcitonin, parathyroid hormone, and denosumab is decided as per the affordability and availability of treatment options. Major gaps still remain in the diagnosis and management of osteoporosis, thus highlighting the need for more structured research in this area. This review focuses on the epidemiology of osteoporosis in Indian women and available treatments. Dove Medical Press 2015-10-19 /pmc/articles/PMC4621228/ /pubmed/26527900 http://dx.doi.org/10.2147/IJWH.S54623 Text en © 2015 Khadilkar and Mandlik. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Khadilkar, Anuradha V
Mandlik, Rubina M
Epidemiology and treatment of osteoporosis in women: an Indian perspective
title Epidemiology and treatment of osteoporosis in women: an Indian perspective
title_full Epidemiology and treatment of osteoporosis in women: an Indian perspective
title_fullStr Epidemiology and treatment of osteoporosis in women: an Indian perspective
title_full_unstemmed Epidemiology and treatment of osteoporosis in women: an Indian perspective
title_short Epidemiology and treatment of osteoporosis in women: an Indian perspective
title_sort epidemiology and treatment of osteoporosis in women: an indian perspective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621228/
https://www.ncbi.nlm.nih.gov/pubmed/26527900
http://dx.doi.org/10.2147/IJWH.S54623
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