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Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda

Background: the James Lind Alliance (JLA) created an approach to elicit the views of those under-represented in research priority exercises. Building on this, the JLA Dementia Priority Setting Partnership was set up as an independent and evidence-based project to identify and prioritise unanswered q...

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Autores principales: Kelly, Sarah, Lafortune, Louise, Hart, Nicola, Cowan, Katherine, Fenton, Mark, Brayne, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621237/
https://www.ncbi.nlm.nih.gov/pubmed/26504119
http://dx.doi.org/10.1093/ageing/afv143
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author Kelly, Sarah
Lafortune, Louise
Hart, Nicola
Cowan, Katherine
Fenton, Mark
Brayne, Carol
author_facet Kelly, Sarah
Lafortune, Louise
Hart, Nicola
Cowan, Katherine
Fenton, Mark
Brayne, Carol
author_sort Kelly, Sarah
collection PubMed
description Background: the James Lind Alliance (JLA) created an approach to elicit the views of those under-represented in research priority exercises. Building on this, the JLA Dementia Priority Setting Partnership was set up as an independent and evidence-based project to identify and prioritise unanswered questions (‘uncertainties') about prevention, diagnosis, treatment and care relating to dementia. Methods: a survey was widely disseminated to stakeholders with an interest in the needs of the older population. Thematic analysis was used to identify themes from the large amount of questions collected from which research questions were developed using PICO framework (Population, Intervention, Comparator, Outcome). Each question was checked against an extensive evidence base of high-quality systematic reviews to verify whether they were true uncertainties. Findings: one thousand five hundred and sixty-three questionnaires were received, from people with dementia, carers/relatives, and health and care professionals; 85 uncertainties were identified from other sources. Questions were refined and formatted iteratively into 146 unique uncertainties. An interim prioritisation process involving diverse organisations identified the top 25 ranked questions. At a final face-to-face prioritisation workshop, 18 people representing the above constituencies arrived by consensus at the top 10 priority questions. The impact of patient and public involvement on the priorities is discussed. Interpretation: the long (146 questions) and top 10 lists of dementia research priorities provide a focus for researchers, funders and commissioners. They highlight a need for more research into care for people with dementia and carers, and a need for high-quality effectiveness trials in all aspects of dementia research.
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spelling pubmed-46212372015-10-27 Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda Kelly, Sarah Lafortune, Louise Hart, Nicola Cowan, Katherine Fenton, Mark Brayne, Carol Age Ageing Research Papers Background: the James Lind Alliance (JLA) created an approach to elicit the views of those under-represented in research priority exercises. Building on this, the JLA Dementia Priority Setting Partnership was set up as an independent and evidence-based project to identify and prioritise unanswered questions (‘uncertainties') about prevention, diagnosis, treatment and care relating to dementia. Methods: a survey was widely disseminated to stakeholders with an interest in the needs of the older population. Thematic analysis was used to identify themes from the large amount of questions collected from which research questions were developed using PICO framework (Population, Intervention, Comparator, Outcome). Each question was checked against an extensive evidence base of high-quality systematic reviews to verify whether they were true uncertainties. Findings: one thousand five hundred and sixty-three questionnaires were received, from people with dementia, carers/relatives, and health and care professionals; 85 uncertainties were identified from other sources. Questions were refined and formatted iteratively into 146 unique uncertainties. An interim prioritisation process involving diverse organisations identified the top 25 ranked questions. At a final face-to-face prioritisation workshop, 18 people representing the above constituencies arrived by consensus at the top 10 priority questions. The impact of patient and public involvement on the priorities is discussed. Interpretation: the long (146 questions) and top 10 lists of dementia research priorities provide a focus for researchers, funders and commissioners. They highlight a need for more research into care for people with dementia and carers, and a need for high-quality effectiveness trials in all aspects of dementia research. Oxford University Press 2015-11 2015-10-26 /pmc/articles/PMC4621237/ /pubmed/26504119 http://dx.doi.org/10.1093/ageing/afv143 Text en © The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Research Papers
Kelly, Sarah
Lafortune, Louise
Hart, Nicola
Cowan, Katherine
Fenton, Mark
Brayne, Carol
Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda
title Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda
title_full Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda
title_fullStr Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda
title_full_unstemmed Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda
title_short Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda
title_sort dementia priority setting partnership with the james lind alliance: using patient and public involvement and the evidence base to inform the research agenda
topic Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621237/
https://www.ncbi.nlm.nih.gov/pubmed/26504119
http://dx.doi.org/10.1093/ageing/afv143
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