uPAR peptide antagonist alters regulation of MAP kinases and Bcl-2 family members in favor of apoptosis in MDA-MB-231 cell line

Urokinase plasminogen activator receptor (uPAR) and its ligands play a major role in many tumors by mediating extracellular matrix degradation and signaling cascades leading to tumor growth, invasion and metastasis. Recently we introduced uPAR decapeptide antagonist with cytotoxic effect on MDA-MB-2...

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Detalles Bibliográficos
Autores principales: Tarighi, P., Montazeri, H., Khorramizadeh, M.R., sobhani, A. Madadkar, Ostad, S.N., Ghahremani, M.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621626/
https://www.ncbi.nlm.nih.gov/pubmed/26600846

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