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Telmisartan induced urticarial vasculitis

A 53-year-old man developed urticarial vasculitis following ingestion of telmisartan and hydrochlorothiazide combination for hypertension. Treatment with prednisolone and cetirizine was curative, but his lesions recurred when he continued telmisartan and hydrochlorothiazide against medical advice. R...

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Autores principales: Mahajan, Vikram K., Singh, Ravinder, Gupta, Mrinal, Raina, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621681/
https://www.ncbi.nlm.nih.gov/pubmed/26600649
http://dx.doi.org/10.4103/0253-7613.165180
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author Mahajan, Vikram K.
Singh, Ravinder
Gupta, Mrinal
Raina, Rashmi
author_facet Mahajan, Vikram K.
Singh, Ravinder
Gupta, Mrinal
Raina, Rashmi
author_sort Mahajan, Vikram K.
collection PubMed
description A 53-year-old man developed urticarial vasculitis following ingestion of telmisartan and hydrochlorothiazide combination for hypertension. Treatment with prednisolone and cetirizine was curative, but his lesions recurred when he continued telmisartan and hydrochlorothiazide against medical advice. Re-challenge with the same doses of telmisartan precipitated similar lesions with telmisartan and not with hydrochlorothiazide. This uncommon cutaneous adverse reaction of angiotensin II receptor blockers has implication for the clinicians as more such cases may become apparent with their wider use than in premarketing studies.
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spelling pubmed-46216812015-11-23 Telmisartan induced urticarial vasculitis Mahajan, Vikram K. Singh, Ravinder Gupta, Mrinal Raina, Rashmi Indian J Pharmacol Drug Watch A 53-year-old man developed urticarial vasculitis following ingestion of telmisartan and hydrochlorothiazide combination for hypertension. Treatment with prednisolone and cetirizine was curative, but his lesions recurred when he continued telmisartan and hydrochlorothiazide against medical advice. Re-challenge with the same doses of telmisartan precipitated similar lesions with telmisartan and not with hydrochlorothiazide. This uncommon cutaneous adverse reaction of angiotensin II receptor blockers has implication for the clinicians as more such cases may become apparent with their wider use than in premarketing studies. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4621681/ /pubmed/26600649 http://dx.doi.org/10.4103/0253-7613.165180 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Mahajan, Vikram K.
Singh, Ravinder
Gupta, Mrinal
Raina, Rashmi
Telmisartan induced urticarial vasculitis
title Telmisartan induced urticarial vasculitis
title_full Telmisartan induced urticarial vasculitis
title_fullStr Telmisartan induced urticarial vasculitis
title_full_unstemmed Telmisartan induced urticarial vasculitis
title_short Telmisartan induced urticarial vasculitis
title_sort telmisartan induced urticarial vasculitis
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621681/
https://www.ncbi.nlm.nih.gov/pubmed/26600649
http://dx.doi.org/10.4103/0253-7613.165180
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