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A case of recurrent agranulocytosis due to levamisole
Agranulocytosis is a rare complication of levamisole. We report a 22-year-old female who developed agranulocytosis due to levamisole. The patient initially presented with salmonellosis and agranulocytosis, and then she recovered with treatment. However, 2 months after discharge, she again presented...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621683/ https://www.ncbi.nlm.nih.gov/pubmed/26600651 http://dx.doi.org/10.4103/0253-7613.165177 |
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author | Ittyachen, Abraham M. Jose, Mohan B. Benjamin, Jobin R. |
author_facet | Ittyachen, Abraham M. Jose, Mohan B. Benjamin, Jobin R. |
author_sort | Ittyachen, Abraham M. |
collection | PubMed |
description | Agranulocytosis is a rare complication of levamisole. We report a 22-year-old female who developed agranulocytosis due to levamisole. The patient initially presented with salmonellosis and agranulocytosis, and then she recovered with treatment. However, 2 months after discharge, she again presented with tonsillitis and agranulocytosis. This time the family revealed that she had been taking levamisole. Though Salmonella infection is a recognized cause of agranulocytosis, any patient presenting with repeated agranulocytosis after an initial recovery should make the clinician suspect another cause, especially drug-induced. A case of Salmonella infection where levamisole was an unsuspecting cause of agranulocytosis has not been described in indexed literature. Recurrent agranulocytosis due to repeated exposure to levamisole has also not been described. |
format | Online Article Text |
id | pubmed-4621683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46216832015-11-23 A case of recurrent agranulocytosis due to levamisole Ittyachen, Abraham M. Jose, Mohan B. Benjamin, Jobin R. Indian J Pharmacol Drug Watch Agranulocytosis is a rare complication of levamisole. We report a 22-year-old female who developed agranulocytosis due to levamisole. The patient initially presented with salmonellosis and agranulocytosis, and then she recovered with treatment. However, 2 months after discharge, she again presented with tonsillitis and agranulocytosis. This time the family revealed that she had been taking levamisole. Though Salmonella infection is a recognized cause of agranulocytosis, any patient presenting with repeated agranulocytosis after an initial recovery should make the clinician suspect another cause, especially drug-induced. A case of Salmonella infection where levamisole was an unsuspecting cause of agranulocytosis has not been described in indexed literature. Recurrent agranulocytosis due to repeated exposure to levamisole has also not been described. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4621683/ /pubmed/26600651 http://dx.doi.org/10.4103/0253-7613.165177 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Drug Watch Ittyachen, Abraham M. Jose, Mohan B. Benjamin, Jobin R. A case of recurrent agranulocytosis due to levamisole |
title | A case of recurrent agranulocytosis due to levamisole |
title_full | A case of recurrent agranulocytosis due to levamisole |
title_fullStr | A case of recurrent agranulocytosis due to levamisole |
title_full_unstemmed | A case of recurrent agranulocytosis due to levamisole |
title_short | A case of recurrent agranulocytosis due to levamisole |
title_sort | case of recurrent agranulocytosis due to levamisole |
topic | Drug Watch |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621683/ https://www.ncbi.nlm.nih.gov/pubmed/26600651 http://dx.doi.org/10.4103/0253-7613.165177 |
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