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A case of recurrent agranulocytosis due to levamisole

Agranulocytosis is a rare complication of levamisole. We report a 22-year-old female who developed agranulocytosis due to levamisole. The patient initially presented with salmonellosis and agranulocytosis, and then she recovered with treatment. However, 2 months after discharge, she again presented...

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Autores principales: Ittyachen, Abraham M., Jose, Mohan B., Benjamin, Jobin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621683/
https://www.ncbi.nlm.nih.gov/pubmed/26600651
http://dx.doi.org/10.4103/0253-7613.165177
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author Ittyachen, Abraham M.
Jose, Mohan B.
Benjamin, Jobin R.
author_facet Ittyachen, Abraham M.
Jose, Mohan B.
Benjamin, Jobin R.
author_sort Ittyachen, Abraham M.
collection PubMed
description Agranulocytosis is a rare complication of levamisole. We report a 22-year-old female who developed agranulocytosis due to levamisole. The patient initially presented with salmonellosis and agranulocytosis, and then she recovered with treatment. However, 2 months after discharge, she again presented with tonsillitis and agranulocytosis. This time the family revealed that she had been taking levamisole. Though Salmonella infection is a recognized cause of agranulocytosis, any patient presenting with repeated agranulocytosis after an initial recovery should make the clinician suspect another cause, especially drug-induced. A case of Salmonella infection where levamisole was an unsuspecting cause of agranulocytosis has not been described in indexed literature. Recurrent agranulocytosis due to repeated exposure to levamisole has also not been described.
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spelling pubmed-46216832015-11-23 A case of recurrent agranulocytosis due to levamisole Ittyachen, Abraham M. Jose, Mohan B. Benjamin, Jobin R. Indian J Pharmacol Drug Watch Agranulocytosis is a rare complication of levamisole. We report a 22-year-old female who developed agranulocytosis due to levamisole. The patient initially presented with salmonellosis and agranulocytosis, and then she recovered with treatment. However, 2 months after discharge, she again presented with tonsillitis and agranulocytosis. This time the family revealed that she had been taking levamisole. Though Salmonella infection is a recognized cause of agranulocytosis, any patient presenting with repeated agranulocytosis after an initial recovery should make the clinician suspect another cause, especially drug-induced. A case of Salmonella infection where levamisole was an unsuspecting cause of agranulocytosis has not been described in indexed literature. Recurrent agranulocytosis due to repeated exposure to levamisole has also not been described. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4621683/ /pubmed/26600651 http://dx.doi.org/10.4103/0253-7613.165177 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Ittyachen, Abraham M.
Jose, Mohan B.
Benjamin, Jobin R.
A case of recurrent agranulocytosis due to levamisole
title A case of recurrent agranulocytosis due to levamisole
title_full A case of recurrent agranulocytosis due to levamisole
title_fullStr A case of recurrent agranulocytosis due to levamisole
title_full_unstemmed A case of recurrent agranulocytosis due to levamisole
title_short A case of recurrent agranulocytosis due to levamisole
title_sort case of recurrent agranulocytosis due to levamisole
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621683/
https://www.ncbi.nlm.nih.gov/pubmed/26600651
http://dx.doi.org/10.4103/0253-7613.165177
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