Hypoglycemic episodes in a case of Prementrual Dysphoric Disorder on sertraline

Sertraline is a selective serotonin reuptake inhibitor. It has been shown to blunt postprandial hyperglycemia in rats and to potentiate the hypoglycemic effects of sulfonylurea agents in humans. Here, we report a case of a 33-year-old nondiabetic patient with no history of glucose intolerance, who e...

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Detalles Bibliográficos
Autores principales: Santra (Dhali), Ranjita, Banerjee, Prithwijit, Munshi, Santanu, Chaudhuri, Patralekha Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621684/
https://www.ncbi.nlm.nih.gov/pubmed/26600652
http://dx.doi.org/10.4103/0253-7613.165193
Descripción
Sumario:Sertraline is a selective serotonin reuptake inhibitor. It has been shown to blunt postprandial hyperglycemia in rats and to potentiate the hypoglycemic effects of sulfonylurea agents in humans. Here, we report a case of a 33-year-old nondiabetic patient with no history of glucose intolerance, who experienced multiple episodes of hypoglycemia that resolved after discontinuation of the drug. Healthcare professionals should consider sertraline among the possible causes of hypoglycemia occurring in patients receiving antidepressants.

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