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Modal affinities of endplate acetylcholine receptors caused by loop C mutations

The time course of the endplate current is determined by the rate and equilibrium constants for acetylcholine receptor (AChR) activation. We measured these constants in single-channel currents from AChRs with mutations at the neurotransmitter-binding sites, in loop C. The main findings are: (a) Almo...

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Detalles Bibliográficos
Autores principales: Vij, Ridhima, Purohit, Prasad, Auerbach, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621750/
https://www.ncbi.nlm.nih.gov/pubmed/26503719
http://dx.doi.org/10.1085/jgp.201511503