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A conserved family of proteins facilitates nascent lipid droplet budding from the ER

Lipid droplets (LDs) are found in all cells and play critical roles in lipid metabolism. De novo LD biogenesis occurs in the endoplasmic reticulum (ER) but is not well understood. We imaged early stages of LD biogenesis using electron microscopy and found that nascent LDs form lens-like structures t...

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Detalles Bibliográficos
Autores principales: Choudhary, Vineet, Ojha, Namrata, Golden, Andy, Prinz, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621845/
https://www.ncbi.nlm.nih.gov/pubmed/26504167
http://dx.doi.org/10.1083/jcb.201505067