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A conserved family of proteins facilitates nascent lipid droplet budding from the ER
Lipid droplets (LDs) are found in all cells and play critical roles in lipid metabolism. De novo LD biogenesis occurs in the endoplasmic reticulum (ER) but is not well understood. We imaged early stages of LD biogenesis using electron microscopy and found that nascent LDs form lens-like structures t...
Autores principales: | Choudhary, Vineet, Ojha, Namrata, Golden, Andy, Prinz, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621845/ https://www.ncbi.nlm.nih.gov/pubmed/26504167 http://dx.doi.org/10.1083/jcb.201505067 |
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