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Histone deacetylase (HDAC)-1, −2, −4 and −6 expression in human pancreatic adenocarcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients’ survival
BACKGROUND: Histone deacetylases (HDACs) have been associated with malignant tumor development and progression in humans. HDAC inhibitors (HDACIs) are currently being explored as anti-cancer agents in clinical trials. The present study aimed to evaluate the clinical significance of HDAC-1, −2, −4 an...
Autores principales: | Giaginis, Constantinos, Damaskos, Christos, Koutsounas, Ioannis, Zizi-Serbetzoglou, Adamantia, Tsoukalas, Nicolaos, Patsouris, Efstratios, Kouraklis, Gregorios, Theocharis, Stamatios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621854/ https://www.ncbi.nlm.nih.gov/pubmed/26502922 http://dx.doi.org/10.1186/s12876-015-0379-y |
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