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Analysis of in vivo turnover of tau in a mouse model of tauopathy

BACKGROUND: Intracellular accumulation of tau as neurofibrillary tangles (NFTs) is the hallmark of Alzheimer’s disease (AD) as well as in other tauopathies. Tau is present not only in the cytoplasm but also in the extracellular space such as cerebrospinal fluid (CSF) and brain interstitial fluid (IS...

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Detalles Bibliográficos
Autores principales:	Yamada, Kaoru, Patel, Tirth K., Hochgräfe, Katja, Mahan, Thomas E., Jiang, Hong, Stewart, Floy R., Mandelkow, Eva-Maria, Holtzman, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621881/ https://www.ncbi.nlm.nih.gov/pubmed/26502977 http://dx.doi.org/10.1186/s13024-015-0052-5

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