Ebselen inhibits QSOX1 enzymatic activity and suppresses invasion of pancreatic and renal cancer cell lines

Quiescin sulfhydryl oxidase 1 (QSOX1) is a highly conserved disulfide bond-generating enzyme that is overexpressed in diverse tumor types. Its enzymatic activity promotes the growth and invasion of tumor cells and alters extracellular matrix composition. In a nude mouse-human tumor xenograft model,...

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Detalles Bibliográficos
Autores principales: Hanavan, Paul D., Borges, Chad R., Katchman, Benjamin A., Faigel, Douglas O., Ho, Thai H., Ma, Chen-Ting, Sergienko, Eduard A., Meurice, Nathalie, Petit, Joachim L., Lake, Douglas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621900/
https://www.ncbi.nlm.nih.gov/pubmed/26158899

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