High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis

The epidermal growth factor receptor (EGFR) is widely overexpressed in esophageal squamous cell carcinoma (ESCC) and it results is associated with a poor prognosis. Identifying the subgroup of ESCC patients who are sensitive to EGFR-targeted therapy is a key point to facilitate its medical use. We r...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chun-yu, Deng, Jia-ying, Cai, Xu-wei, Fu, Xiao-long, Li, Yuan, Zhou, Xiao-yan, Wu, Xiang-hua, Hu, Xi-chun, Fan, Min, Xiang, Jia-qing, Zhang, Ya-wei, Chen, Hai-quan, Perez, Rolando, Jiang, Guo-liang, Zhao, Kuai-le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621919/
https://www.ncbi.nlm.nih.gov/pubmed/26124180

Ejemplares similares

Ejemplares similares