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Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization

Bcl–2 is an anti-apoptotic protein with important roles in vascular homeostasis and angiogenesis. Mice globally lacking Bcl–2 (Bcl–2 -/-) are small in stature and succumb to renal failure shortly after weaning as a result of renal hypoplasia/cystic dysplasia. We have shown that Bcl–2 -/- mice displa...

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Detalles Bibliográficos
Autores principales:	Zaitoun, Ismail S., Johnson, Ryan P., Jamali, Nasim, Almomani, Reem, Wang, Shoujian, Sheibani, Nader, Sorenson, Christine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622043/ https://www.ncbi.nlm.nih.gov/pubmed/26444547 http://dx.doi.org/10.1371/journal.pone.0139994

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