Raman spectroscopy characterization of antibody phases in serum

When administered in serum, an efficacious therapeutic antibody should be homogeneous to minimize immune reactions or injection site irritation during administration. Monoclonal antibody (mAb) phase separation is one type of inhomogeneity observed in serum, and thus screening potential phase separat...

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Detalles Bibliográficos
Autores principales: Baker, Audrey E, Mantz, Amber R, Chiu, Mark L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622053/
https://www.ncbi.nlm.nih.gov/pubmed/25484036
http://dx.doi.org/10.4161/19420862.2014.975100

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