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Raman spectroscopy characterization of antibody phases in serum
When administered in serum, an efficacious therapeutic antibody should be homogeneous to minimize immune reactions or injection site irritation during administration. Monoclonal antibody (mAb) phase separation is one type of inhomogeneity observed in serum, and thus screening potential phase separat...
Autores principales: | Baker, Audrey E, Mantz, Amber R, Chiu, Mark L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622053/ https://www.ncbi.nlm.nih.gov/pubmed/25484036 http://dx.doi.org/10.4161/19420862.2014.975100 |
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