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Attenuation of Replication-Competent Adenovirus Serotype 26 Vaccines by Vectorization

Replication-competent adenovirus (rcAd)-based vaccine vectors may theoretically provide immunological advantages over replication-incompetent Ad vectors, but they also raise additional potential clinical and regulatory issues. We produced replication-competent Ad serotype 26 (rcAd26) vectors by addi...

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Detalles Bibliográficos
Autores principales: Maxfield, Lori F., Abbink, Peter, Stephenson, Kathryn E., Borducchi, Erica N., Ng'ang'a, David, Kirilova, Marinela M., Paulino, Noelix, Boyd, Michael, Shabram, Paul, Ruan, Qian, Patel, Mayank, Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622110/
https://www.ncbi.nlm.nih.gov/pubmed/26376928
http://dx.doi.org/10.1128/CVI.00510-15