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RmtC and RmtF 16S rRNA Methyltransferase in NDM-1–Producing Pseudomonas aeruginosa

We investigated 16S rRNA methyltransferases in 38 bla(NDM-1)–positive Pseudomonas aeruginosa isolates and found RmtC in 3 isolates, 1 of which also harbored RmtF. The isolates were clonally unrelated; rmtC and rmtF genes were located on a chromosome with the bla(NDM-1) gene. Strategies are needed to...

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Detalles Bibliográficos
Autores principales: Rahman, Mohibur, Prasad, Kashi Nath, Pathak, Ashutosh, Pati, Binod Kumar, Singh, Avinash, Ovejero, Cristina M., Ahmad, Saheem, Gonzalez-Zorn, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622239/
https://www.ncbi.nlm.nih.gov/pubmed/26488937
http://dx.doi.org/10.3201/eid2111.150271
Descripción
Sumario:We investigated 16S rRNA methyltransferases in 38 bla(NDM-1)–positive Pseudomonas aeruginosa isolates and found RmtC in 3 isolates, 1 of which also harbored RmtF. The isolates were clonally unrelated; rmtC and rmtF genes were located on a chromosome with the bla(NDM-1) gene. Strategies are needed to limit the spread of such isolates.