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No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010
Associations between Lyme disease and certain neurodegenerative diseases have been proposed, but supportive evidence for an association is lacking. Similar geographic distributions would be expected if 2 conditions were etiologically linked. Thus, we compared the distribution of Lyme disease cases i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622257/ https://www.ncbi.nlm.nih.gov/pubmed/26488307 http://dx.doi.org/10.3201/eid2111.150778 |
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author | Forrester, Joseph D. Kugeler, Kiersten J. Perea, Anna E. Pastula, Daniel M. Mead, Paul S. |
author_facet | Forrester, Joseph D. Kugeler, Kiersten J. Perea, Anna E. Pastula, Daniel M. Mead, Paul S. |
author_sort | Forrester, Joseph D. |
collection | PubMed |
description | Associations between Lyme disease and certain neurodegenerative diseases have been proposed, but supportive evidence for an association is lacking. Similar geographic distributions would be expected if 2 conditions were etiologically linked. Thus, we compared the distribution of Lyme disease cases in the United States with the distributions of deaths due to Alzheimer disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and Parkinson disease; no geographic correlations were identified. Lyme disease incidence per US state was not correlated with rates of death due to ALS, MS, or Parkinson disease; however, an inverse correlation was detected between Lyme disease and Alzheimer disease. The absence of a positive correlation between the geographic distribution of Lyme disease and the distribution of deaths due to Alzheimer disease, ALS, MS, and Parkinson disease provides further evidence that Lyme disease is not associated with the development of these neurodegenerative conditions. |
format | Online Article Text |
id | pubmed-4622257 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-46222572015-11-02 No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010 Forrester, Joseph D. Kugeler, Kiersten J. Perea, Anna E. Pastula, Daniel M. Mead, Paul S. Emerg Infect Dis Research Associations between Lyme disease and certain neurodegenerative diseases have been proposed, but supportive evidence for an association is lacking. Similar geographic distributions would be expected if 2 conditions were etiologically linked. Thus, we compared the distribution of Lyme disease cases in the United States with the distributions of deaths due to Alzheimer disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and Parkinson disease; no geographic correlations were identified. Lyme disease incidence per US state was not correlated with rates of death due to ALS, MS, or Parkinson disease; however, an inverse correlation was detected between Lyme disease and Alzheimer disease. The absence of a positive correlation between the geographic distribution of Lyme disease and the distribution of deaths due to Alzheimer disease, ALS, MS, and Parkinson disease provides further evidence that Lyme disease is not associated with the development of these neurodegenerative conditions. Centers for Disease Control and Prevention 2015-11 /pmc/articles/PMC4622257/ /pubmed/26488307 http://dx.doi.org/10.3201/eid2111.150778 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Forrester, Joseph D. Kugeler, Kiersten J. Perea, Anna E. Pastula, Daniel M. Mead, Paul S. No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010 |
title | No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010 |
title_full | No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010 |
title_fullStr | No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010 |
title_full_unstemmed | No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010 |
title_short | No Geographic Correlation between Lyme Disease and Death Due to 4 Neurodegenerative Disorders, United States, 2001–2010 |
title_sort | no geographic correlation between lyme disease and death due to 4 neurodegenerative disorders, united states, 2001–2010 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622257/ https://www.ncbi.nlm.nih.gov/pubmed/26488307 http://dx.doi.org/10.3201/eid2111.150778 |
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