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Glutathione-degradable drug-loaded nanogel effectively and securely suppresses hepatoma in mouse model
The reduction-responsive polymeric nanocarriers have attracted considerable interest because of a significantly higher concentration of intracellular glutathione in comparison with that outside cells. The smart nanovehicles can selectively transport the antitumor drugs into cells to improve efficaci...
Autores principales: | Liu, Xingang, Wang, Jianmeng, Xu, Weiguo, Ding, Jianxun, Shi, Bo, Huang, Kexin, Zhuang, Xiuli, Chen, Xuesi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622485/ https://www.ncbi.nlm.nih.gov/pubmed/26543363 http://dx.doi.org/10.2147/IJN.S90000 |
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