Cargando…

Zabofloxacin versus moxifloxacin in patients with COPD exacerbation: a multicenter, double-blind, double-dummy, randomized, controlled, Phase III, non-inferiority trial

A new quinolone, zabofloxacin, has now been developed; hence, a non-inferiority trial is needed to compare this new compound with another widely used quinolone to examine its efficacy and safety for the treatment of chronic obstructive pulmonary disease (COPD) exacerbations. This was a prospective,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rhee, Chin Kook, Chang, Jung Hyun, Choi, Eu gene, Kim, Hyun kuk, Kwon, Yong-Soo, Kyung, Sun Young, Lee, Ji-Hyun, Park, Myung Jae, Yoo, Kwang Ha, Oh, Yeon Mok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622522/ https://www.ncbi.nlm.nih.gov/pubmed/26543359 http://dx.doi.org/10.2147/COPD.S90948

Ejemplares similares

Moxifloxacin in the management of exacerbations of chronic bronchitis and COPD
por: Miravitlles, Marc
Publicado: (2007)

Delafloxacin, Finafloxacin, and Zabofloxacin: Novel Fluoroquinolones in the Antibiotic Pipeline
por: Kocsis, Béla, et al.
Publicado: (2021)

Antimicrobial Activity of Zabofloxacin against Clinically Isolated Streptococcus pneumoniae
por: Park, Hee-Soo, et al.
Publicado: (2016)

Efficacy and Safety of Naftopidil in Patients With Neurogenic Lower Urinary Tract Dysfunction: An 8-Week, Active-Controlled, Stratified-Randomized, Double-Blind, Double-Dummy, Parallel Group, Noninferiority, Multicenter Design
por: Sung, Hyun Hwan, et al.
Publicado: (2020)

Moxifloxacin versus amoxicillin/clavulanic acid in outpatient acute exacerbations of COPD: MAESTRAL results
por: Wilson, Robert, et al.
Publicado: (2012)

The safety and efficacy of CKD-497 in patients with acute upper respiratory tract infection and bronchitis symptoms: a multicenter, double-blind, double-dummy, randomized, controlled, phase II clinical trial
por: Ra, Seung Won, et al.
Publicado: (2021)

Comparison of Korean COPD Guideline and GOLD Initiative Report in Term of Acute Exacerbation: A Validation Study for Korean COPD Guideline
por: Hwang, Yong Il, et al.
Publicado: (2014)

Comparison of the efficacy and safety of CELBESTA® versus CELEBREX® in patients with rheumatoid arthritis: a 6-week, multicenter, double-blind, double-dummy, active-controlled, randomized, parallel-group, non-inferiority phase 4 clinical trial
por: Kim, Hyun-Sook, et al.
Publicado: (2020)

The association between eosinophilic exacerbation and eosinophilic levels in stable COPD
por: Kang, Hye Seon, et al.
Publicado: (2021)

Comparison of Two pMDIs in Adult Asthmatics: A Randomized Double-Blind Double-Dummy Clinical Trial
por: Nam, Tae-Hyun, et al.
Publicado: (2022)

Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin
por: Kocsis, Bela, et al.
Publicado: (2016)

A Randomized Double-Blind, Double-Dummy, Multicenter Trial of Azasetron versus Ondansetron to Evaluate Efficacy and Safety in the Prevention of Delayed Nausea and Vomiting Induced by Chemotherapy
por: Lee, Hee Yeon, et al.
Publicado: (2014)

Chuanhu Anti-Gout Mixture versus Colchicine for Acute Gouty Arthritis: A Randomized, Double-Blind, Double-Dummy, Non-Inferiority Trial
por: Wang, YanGang, et al.
Publicado: (2014)

Efficacy and safety of moxifloxacin in acute exacerbations of chronic bronchitis: a prospective, multicenter, observational study (AVANTI)
por: Chuchalin, Alexander, et al.
Publicado: (2013)

Treatment of Bacterial Vaginosis: A Multicenter, Double-Blind, Double-Dummy, Randomised Phase III Study Comparing Secnidazole and Metronidazole
por: Bohbot, Jean-Marc, et al.
Publicado: (2010)

Zhengtian Capsule versus flunarizine in patients with migraine: a multi-center, double-blind, double-dummy, randomized controlled, non-inferior clinical trial
por: Cao, Kegang, et al.
Publicado: (2016)

Comparison of the clinical characteristics and treatment outcomes of patients requiring hospital admission to treat eosinophilic and neutrophilic exacerbations of COPD
por: Kang, Hye Seon, et al.
Publicado: (2016)

Reduction of corticosteroid use in outpatient treatment of exacerbated COPD - Study protocol for a randomized, double-blind, non-inferiority study, (The RECUT-trial)
por: Urwyler, Pascal, et al.
Publicado: (2019)

In Vitro and In Vivo Activity of Zabofloxacin and Other Fluoroquinolones Against MRSA Isolates from A University Hospital in Egypt
por: MOHAMED, NELLY M., et al.
Publicado: (2019)

Post Hoc Assessment of Time to Clinical Response Among Adults Hospitalized with Community-Acquired Bacterial Pneumonia Who Received Either Lefamulin or Moxifloxacin in 2 Phase III Randomized, Double-Blind, Double-Dummy Clinical Trials
por: Lodise, Thomas, et al.
Publicado: (2020)

Effect of Broncho-Vaxom (OM-85) on the frequency of chronic obstructive pulmonary disease (COPD) exacerbations
por: Choi, Joon Young, et al.
Publicado: (2023)

Once daily versus three times daily mesalazine granules in active ulcerative colitis: a double-blind, double-dummy, randomised, non-inferiority trial
por: Kruis, W, et al.
Publicado: (2009)

Impacts of coexisting bronchial asthma on severe exacerbations in mild-to-moderate COPD: results from a national database
por: Lee, Hyun, et al.
Publicado: (2016)

Budesonide/formoterol as effective as prednisolone plus formoterol in acute exacerbations of COPD A double-blind, randomised, non-inferiority, parallel-group, multicentre study
por: Ställberg, Björn, et al.
Publicado: (2009)

Efficacy of DA-9701 (Motilitone) in Functional Dyspepsia Compared to Pantoprazole: A Multicenter, Randomized, Double-blind, Non-inferiority Study
por: Jung, Hye-Kyung, et al.
Publicado: (2016)

A double-blind, double-dummy, randomized controlled, multicenter trial of (99)Tc-methylene diphosphonate in patients with moderate to severe rheumatoid arthritis
por: Fu, Qiong, et al.
Publicado: (2021)

Efficacy and Safety of Qinpi Tongfeng Formula in the Treatment of Acute Gouty Arthritis: A Double-Blind, Double-Dummy, Multicenter, Randomized Controlled Trial
por: Fan, Yihua, et al.
Publicado: (2022)

Factors associated with chronic obstructive pulmonary disease exacerbation, based on big data analysis
por: Lee, Jongmin, et al.
Publicado: (2019)

Efficacy and Safety of Tiropramide in the Treatment of Patients With Irritable Bowel Syndrome: A Multicenter, Randomized, Double-blind, Non-inferiority Trial, Compared With Octylonium
por: Lee, Kang Nyeong, et al.
Publicado: (2014)

Prevention of COPD exacerbation by lysozyme: a double-blind, randomized, placebo-controlled study
por: Fukuchi, Yoshinosuke, et al.
Publicado: (2016)

Moxifloxacin in the Outpatient Treatment of Moderate Exacerbations of Chronic Obstructive Pulmonary Disease
por: Minov, Jordan, et al.
Publicado: (2018)

Effect of an Echinacea-Based Hot Drink Versus Oseltamivir in Influenza Treatment: A Randomized, Double-Blind, Double-Dummy, Multicenter, Noninferiority Clinical Trial
por: Rauš, Karel, et al.
Publicado: (2015)

Tenofovir disoproxil fumarate in Chinese chronic hepatitis B patients: Results of a multicenter, double-blind, double-dummy, clinical trial at 96 weeks
por: Chen, Xiao-Fan, et al.
Publicado: (2021)

Health-Related Quality of Life as Measured by the 12-Item Short-Form Survey Among Adults With Community-Acquired Bacterial Pneumonia who Received Either Lefamulin or Moxifloxacin in 2 Phase III Randomized, Double-Blind, Double-Dummy Clinical Trials
por: Lodise, Thomas P, et al.
Publicado: (2020)

Double Fracture of the Inferior Maxilla
por: Wylie, J. L.
Publicado: (1866)

Menatetrenone versus alfacalcidol in the treatment of Chinese postmenopausal women with osteoporosis: a multicenter, randomized, double-blinded, double-dummy, positive drug-controlled clinical trial
por: Jiang, Yan, et al.
Publicado: (2014)

Jintiange combined with alfacalcidol improves muscle strength and balance in primary osteoporosis: A randomized, double-blind, double-dummy, positive-controlled, multicenter clinical trial
por: Liang, Hanting, et al.
Publicado: (2022)

A Randomized, Multicenter, Double-Blind, Parallel, Non-Inferiority Clinical Study to Compare the Efficacy and Safety of Unicenta and Melsmon for Menopausal Symptom Improvement
por: Kim, Seongmin, et al.
Publicado: (2023)

Air Trapping and the Risk of COPD Exacerbation: Analysis From Prospective KOCOSS Cohort
por: Kim, Youlim, et al.
Publicado: (2022)

Revised (2018) COPD Clinical Practice Guideline of the Korean Academy of Tuberculosis and Respiratory Disease: A Summary
por: Park, Yong-Bum, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4e7747i3sl7ndhd76rovjplq3n