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Aggregation risk prediction for antibodies and its application to biotherapeutic development
Aggregation is a common problem affecting biopharmaceutical development that can have a significant effect on the quality of the product, as well as the safety to patients, particularly because of the increased risk of immune reactions. Here, we describe a new high-throughput screening algorithm dev...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622581/ https://www.ncbi.nlm.nih.gov/pubmed/25760769 http://dx.doi.org/10.1080/19420862.2015.1007828 |