Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia

Although children with acute lymphoblastic leukemia (ALL) generally have a good outcome, some patients do relapse and survival following relapse is poor. Altered DNA methylation is highly prevalent in ALL and raises the possibility that DNA methylation-based biomarkers could predict patient outcome....

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Detalles Bibliográficos
Autores principales: Gabriel, Alem S, Lafta, Fadhel M, Schwalbe, Edward C, Nakjang, Sirintra, Cockell, Simon J, Iliasova, Alice, Enshaei, Amir, Schwab, Claire, Rand, Vikki, Clifford, Steven C, Kinsey, Sally E, Mitchell, Chris D, Vora, Ajay, Harrison, Christine J, Moorman, Anthony V, Strathdee, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622588/
https://www.ncbi.nlm.nih.gov/pubmed/26237075
http://dx.doi.org/10.1080/15592294.2015.1061174

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