Cargando…
Macrophages are critical effectors of antibody therapies for cancer
Macrophages are innate immune cells that derive from circulating monocytes, reside in all tissues, and participate in many states of pathology. Macrophages play a dichotomous role in cancer, where they promote tumor growth but also serve as critical immune effectors of therapeutic antibodies. Macrop...
Autores principales: | Weiskopf, Kipp, Weissman, Irving L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622600/ https://www.ncbi.nlm.nih.gov/pubmed/25667985 http://dx.doi.org/10.1080/19420862.2015.1011450 |
Ejemplares similares
-
CD47-blocking therapies stimulate macrophage cytokine secretion and are effective in a model of peritoneal carcinomatosis
por: Weiskopf, Kipp, et al.
Publicado: (2015) -
Flipping the script on macrophages in leiomyosarcoma
por: Edris, Badreddin, et al.
Publicado: (2012) -
Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants
por: Weiskopf, Kipp, et al.
Publicado: (2013) -
Engineered therapeutic antibodies with enhanced effector functions: Clinical application of the Potelligent® Technology
por: Matsushita, Takefumi
Publicado: (2011) -
Use of a KIT-specific monoclonal antibody to bypass imatinib resistance in gastrointestinal stromal tumors
por: Edris, Badreddin, et al.
Publicado: (2013)