Cargando…

Efficient generation of monoclonal antibodies from single rhesus macaque antibody secreting cells

Nonhuman primates (NHPs) are used as a preclinical model for vaccine development, and the antibody profiles to experimental vaccines in NHPs can provide critical information for both vaccine design and translation to clinical efficacy. However, an efficient protocol for generating monoclonal antibod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Weixu, Li, Leike, Xiong, Wei, Fan, Xuejun, Deng, Hui, Bett, Andrew J, Chen, Zhifeng, Tang, Aimin, Cox, Kara S, Joyce, Joseph G, Freed, Daniel C, Thoryk, Elizabeth, Fu, Tong-Ming, Casimiro, Danilo R, Zhang, Ningyan, A Vora, Kalpit, An, Zhiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622687/ https://www.ncbi.nlm.nih.gov/pubmed/25996084 http://dx.doi.org/10.1080/19420862.2015.1051440

Ejemplares similares

Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes
por: Li, Leike, et al.
Publicado: (2019)

Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein
por: Chen, Zhifeng, et al.
Publicado: (2016)

Targeting Human-Cytomegalovirus-Infected Cells by Redirecting T Cells Using an Anti-CD3/Anti-Glycoprotein B Bispecific Antibody
por: Meng, Weixu, et al.
Publicado: (2017)

Phenotypic Characterization of Chinese Rhesus Macaque Plasmablasts for Cloning Antigen-Specific Monoclonal Antibodies
por: Zhang, Fan, et al.
Publicado: (2019)

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques
por: Broeckel, Rebecca, et al.
Publicado: (2017)

Rapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell cultures
por: Cox, Kara S., et al.
Publicado: (2015)

Focusing antibody responses to the fusion peptide in rhesus macaques
por: Cottrell, Christopher A., et al.
Publicado: (2023)

Co-Administration of Lipid Nanoparticles and Sub-Unit Vaccine Antigens Is Required for Increase in Antigen-Specific Immune Responses in Mice
por: Thoryk, Elizabeth A., et al.
Publicado: (2016)

Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response
por: Chen, Zhifeng, et al.
Publicado: (2018)

Characterisation of mouse monoclonal antibodies against rhesus macaque killer immunoglobulin-like receptors KIR3D
por: Hermes, Meike, et al.
Publicado: (2012)

Phenotypic and Functional Characterization of Monoclonal Antibodies with Specificity for Rhesus Macaque CD200, CD200R and Mincle
por: Byrareddy, Siddappa N., et al.
Publicado: (2015)

The Cytokine Response Profile of Ebola Virus Disease in a Large Cohort of Rhesus Macaques Treated With Monoclonal Antibodies
por: Banadyga, Logan, et al.
Publicado: (2019)

Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin
por: Roy, Chad J., et al.
Publicado: (2020)

A SMART method for efficiently isolating monoclonal antibodies from individual rhesus macaque memory B cells
por: Weinfurter, Jason T., et al.
Publicado: (2023)

A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial
por: Li, Leike, et al.
Publicado: (2021)

Biodistribution of neutralizing monoclonal antibodies IgG1 b12 and LALA in mucosal and lymphatic tissues of rhesus macaques
por: Hessell, AJ, et al.
Publicado: (2012)

Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation
por: Verma, Anil, et al.
Publicado: (2021)

Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice
por: Zhao, Peng, et al.
Publicado: (2022)

Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques
por: Pollara, Justin, et al.
Publicado: (2021)

Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection
por: Valencia, Sarah M., et al.
Publicado: (2023)

Characterization of potent RSV neutralizing antibodies isolated from human memory B cells and identification of diverse RSV/hMPV cross-neutralizing epitopes
por: Xiao, Xiao, et al.
Publicado: (2019)

A Tetravalent Sub-unit Dengue Vaccine Formulated with Ionizable Cationic Lipid Nanoparticle induces Significant Immune Responses in Rodents and Non-Human Primates
por: Swaminathan, Gokul, et al.
Publicado: (2016)

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques
por: Wen, Jing, et al.
Publicado: (2021)

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques
por: Zhao, Fangzhu, et al.
Publicado: (2020)

Effective Treatment of Staphylococcal Enterotoxin B Aerosol Intoxication in Rhesus Macaques by Using Two Parenterally Administered High-Affinity Monoclonal Antibodies
por: Verreault, Daniel, et al.
Publicado: (2019)

Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies
por: Wrapp, Daniel, et al.
Publicado: (2022)

Profiling of hMPV F-specific antibodies isolated from human memory B cells
por: Xiao, Xiao, et al.
Publicado: (2022)

Pharmacokinetics and Immunogenicity of Broadly Neutralizing HIV Monoclonal Antibodies in Macaques
por: Rosenberg, Yvonne, et al.
Publicado: (2015)

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques
por: Santra, Sampa, et al.
Publicado: (2015)

1644. A Potent Broadly Neutralizing Antibody Isolated From Human Memory B-cells Binding to Conserved Site IV on the RSV F Protein
por: Vora, Kalpit, et al.
Publicado: (2018)

Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies
por: Hora, Bhavna, et al.
Publicado: (2023)

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
por: He, Wan-ting, et al.
Publicado: (2022)

Induction of Antibodies in Rhesus Macaques That Recognize a Fusion-Intermediate Conformation of HIV-1 gp41
por: Dennison, S. Moses, et al.
Publicado: (2011)

Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step
por: Ye, Xiaohua, et al.
Publicado: (2020)

Anti-GRP-R monoclonal antibody antitumor therapy against neuroblastoma
por: Qiao, Jingbo, et al.
Publicado: (2022)

Anti-α(4)β(7) monoclonal antibody–conjugated nanoparticles block integrin α(4)β(7) on intravaginal T cells in rhesus macaques
por: Yang, Sidi, et al.
Publicado: (2020)

A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein
por: Tang, Aimin, et al.
Publicado: (2019)

Non-neutralizing Antibodies May Contribute to Suppression of SIVmac239 Viremia in Indian Rhesus Macaques
por: Pedreño-Lopez, Nuria, et al.
Publicado: (2021)

CD4+ T Cells Are Dispensable for Induction of Broad Heterologous HIV Neutralizing Antibodies in Rhesus Macaques
por: Sarkar, Sanghita, et al.
Publicado: (2021)

Enhanced dengue vaccine virus replication and neutralizing antibody responses in immune primed rhesus macaques
por: McCracken, Michael K., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qbn7jfp6c7e5n8luo2voo46db2