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Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodies
Functional knockdowns mediated by endoplasmatic reticulum-retained antibodies (ER intrabodies) are a promising tool for research because they allow functional interference on the protein level. We demonstrate for the first time that ER intrabodies can induce a knock-down phenotype in mice. Surface V...
Autores principales: | Marschall, Andrea LJ, Single, Frank N, Schlarmann, Katrin, Bosio, Andreas, Strebe, Nina, van den Heuvel, Joop, Frenzel, André, Dübel, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622715/ https://www.ncbi.nlm.nih.gov/pubmed/25484057 http://dx.doi.org/10.4161/mabs.34377 |
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