LINE-1 methylation in granulocyte DNA and trihalomethane exposure is associated with bladder cancer risk

DNA methylation changes contribute to bladder carcinogenesis. Trihalomethanes (THM), a class of disinfection by-products, are associated with increased urothelial bladder cancer (UBC) risk. THM exposure in animal models produces DNA hypomethylation. We evaluated the relationship of LINE-1 5-methylcy...

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Detalles Bibliográficos
Autores principales: Salas, Lucas A, Villanueva, Cristina M, Tajuddin, Salman M, Amaral, André F S, Fernandez, Agustín F, Moore, Lee E, Carrato, Alfredo, Tardón, Adonina, Serra, Consol, García-Closas, Reina, Basagaña, Xavier, Rothman, Nathaniel, Silverman, Debra T, Cantor, Kenneth P, Kogevinas, Manolis, Real, Francisco X, Fraga, Mario F, Malats, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622716/
https://www.ncbi.nlm.nih.gov/pubmed/25482586
http://dx.doi.org/10.4161/15592294.2014.983377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622716/
https://www.ncbi.nlm.nih.gov/pubmed/25482586
http://dx.doi.org/10.4161/15592294.2014.983377

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